Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTAFR | P25105 | 10/20 | 0.55 |
| ▸ | HRH1 | P35367 | 4/20 | 0.53 |
| ▸ | FNTA | P49354 | 5/20 | 0.51 |
| ▸ | FNTB | P49356 | 5/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.48 |
| ▸ | HTR2A | P28223 | 2/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.48 |
| ▸ | HTR2B | P41595 | 2/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | HTR2C | P28335 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | SLC6A15 | Q9H2J7 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.43 |
| ▸ | GMNN | O75496 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9333178 | 0.93 | FNTA (0.46) | PTAFRHRH1FNTAFNTB | |
| SCHEMBL9333282 | 0.92 | PTAFR (0.59) | PTAFRHRH1FNTAFNTBCHRM2 | |
| SCHEMBL9332876 | 0.91 | FNTA (0.65) | PTAFRHRH1FNTAFNTBCHRM2 | |
| SCHEMBL9333210 | 0.84 | FNTA (0.52) | PTAFRHRH1FNTAFNTBCHRM2 | |
| SCHEMBL9332766 | 0.84 | FNTA (0.52) | PTAFRHRH1FNTAFNTBCHRM2 | |
| SCHEMBL9332755 | 0.83 | FNTA (0.63) | PTAFRHRH1FNTAFNTBCHRM2 | |
| SCHEMBL9332709 | 0.81 | FNTA (0.63) | PTAFRHRH1FNTAFNTBCHRM2 | |
| SCHEMBL9705980 | 0.81 | FNTA (0.48) | PTAFRHRH1FNTAFNTBCHRM2 | |
| SCHEMBL9332847 | 0.80 | DRD3 (0.51) | HRH1CHRM2HTR2AOPRK1HTR2B | |
| SCHEMBL9333208 | 0.80 | HRH1 (0.44) | HRH1FNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0572425-B1 | IMIDAZOPYRIDINE PAF/H 1 ANTAGONISTS | PFIZER LTD (GB) | 1994-08-03 | — | — | EP | disclosed |