Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.62 |
| ▸ | CA1 | P00915 | 2/20 | 0.57 |
| ▸ | CA2 | P00918 | 2/20 | 0.57 |
| ▸ | CA9 | Q16790 | 2/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.45 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.43 |
| ▸ | FSCN1 | Q16658 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2434637 | 0.83 | GRIK1 (0.49) | KDM4EHSD17B10NPC1RAB9APOLB | |
| SCHEMBL3782005 | 0.82 | KDM4E (0.68) | KDM4EHSD17B10CA1CA2CA9 | |
| SCHEMBL22501545 | 0.82 | CA1 (0.54) | KDM4EHSD17B10CA1CA2CA9 | |
| SCHEMBL13283740 | 0.81 | NPC1 (0.50) | KDM4EHSD17B10CA1CA2CA9 | |
| SCHEMBL11636436 | 0.81 | KDM4E (0.71) | KDM4EHSD17B10CA1CA2CA9 | |
| SCHEMBL29822237 | 0.81 | KDM4E (0.66) | KDM4EHSD17B10CA1CA2CA9 | |
| SCHEMBL4311940 | 0.81 | KDM4E (0.66) | KDM4EHSD17B10CA1CA2CA9 | |
| SCHEMBL10852754 | 0.81 | CA1 (0.60) | KDM4EHSD17B10CA1CA2CA9 | |
| SCHEMBL15643309 | 0.81 | ALDH1A1 (0.57) | KDM4EHSD17B10NPC1RAB9APOLB | |
| SCHEMBL1952367 | 0.79 | POLB (0.67) | KDM4EHSD17B10CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0376103-B1 | A 2-acylamino-5-halogenated-cinnamic acid derivative and method for its production | NIPPON KAYAKU KK (JP) | 1994-04-20 | — | — | EP | disclosed |
| US-4997972-A | 2-acylamino-5-halogenated-cinnamic acid derivative and method for its production | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1991-03-05 | — | — | US | disclosed |
| EP-0376103-A1 | A 2-acylamino-5-halogenated-cinnamic acid derivative and method for its production | Nippon Kayaku Kabushiki Kaisha (JP) | 1990-07-04 | — | — | EP | disclosed |