Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 9/20 | 0.76 |
| ▸ | RAB9A | P51151 | 8/20 | 0.76 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.76 |
| ▸ | TP53 | P04637 | 2/20 | 0.76 |
| ▸ | TSHR | P16473 | 2/20 | 0.71 |
| ▸ | CASP2 | P42575 | 1/20 | 0.69 |
| ▸ | CSNK1D | P48730 | 6/20 | 0.67 |
| ▸ | POLB | P06746 | 1/20 | 0.65 |
| ▸ | HTT | P42858 | 2/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.65 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.61 |
| ▸ | SCD | O00767 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9335241 | 0.91 | NPC1 (0.79) | NPC1RAB9ASMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL9332358 | 0.90 | NPC1 (0.77) | NPC1RAB9ASMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL9332924 | 0.86 | NPC1 (0.72) | NPC1RAB9ASMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL9332634 | 0.84 | SCD (0.71) | NPC1RAB9ASMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL9332913 | 0.83 | CASP2 (0.79) | NPC1RAB9ASMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL7933605 | 0.82 | CASP2 (0.77) | NPC1RAB9ASMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL20543332 | 0.82 | CASP2 (1.00) | NPC1RAB9ASMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL7786534 | 0.82 | CASP2 (0.77) | NPC1RAB9ASMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL5653636 | 0.82 | CASP2 (0.77) | NPC1RAB9ASMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL29500248 | 0.82 | CASP2 (0.77) | NPC1RAB9ASMN1; SMN2ALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0397169-B1 | Novel benzothiazole derivatives | TOYO BOSEKI (JP) | 1994-04-13 | — | — | EP | claimed |
| US-5036086-A | Novel benzothiazole derivatives | TOYO BOSEKI KABUSHIKI KAISHA (JP) | 1991-07-30 | — | — | US | claimed |
| EP-0397169-A1 | Novel benzothiazole derivatives | TOYO BOSEKI KABUSHIKI KAISHA Trading under the name of Toyobo Co., Ltd. (JP) | 1990-11-14 | — | — | EP | claimed |
| EP-0397169-B1 | Novel benzothiazole derivatives | TOYO BOSEKI (JP) | 1994-04-13 | — | — | EP | disclosed |
| US-5036086-A | Novel benzothiazole derivatives | TOYO BOSEKI KABUSHIKI KAISHA (JP) | 1991-07-30 | — | — | US | disclosed |
| EP-0397169-A1 | Novel benzothiazole derivatives | TOYO BOSEKI KABUSHIKI KAISHA Trading under the name of Toyobo Co., Ltd. (JP) | 1990-11-14 | — | — | EP | disclosed |