Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 13/20 | 0.63 |
| ▸ | CASP2 | P42575 | 1/20 | 0.52 |
| ▸ | FAAH | O00519 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | NAAA | Q02083 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9333202 | 0.98 | EPHX1 (0.67) | EPHX1CASP2FAAHSMN1; SMN2ALDH1A1 | |
| SCHEMBL28941966 | 0.94 | EPHX1 (0.57) | EPHX1CASP2FAAHSMN1; SMN2ALDH1A1 | |
| SCHEMBL1964189 | 0.85 | EPHX1 (0.48) | EPHX1SMN1; SMN2ALDH1A1 | |
| SCHEMBL28303861 | 0.84 | EPHX1 (0.69) | EPHX1CASP2ALDH1A1NAAAMEN1 | |
| SCHEMBL4911114 | 0.83 | ALDH1A1 (0.73) | EPHX1CASP2FAAHSMN1; SMN2ALDH1A1 | |
| SCHEMBL19336851 | 0.83 | EPHX1 (0.82) | EPHX1CASP2ALDH1A1NAAA | |
| SCHEMBL11252841 | 0.82 | EPHX1 (0.67) | EPHX1CASP2FAAHNAAA | |
| SCHEMBL11257359 | 0.82 | EPHX1 (0.67) | EPHX1CASP2FAAHNAAA | |
| SCHEMBL15856106 | 0.81 | ALDH1A1 (0.77) | EPHX1CASP2FAAHSMN1; SMN2ALDH1A1 | |
| SCHEMBL20456253 | 0.81 | ALDH1A1 (0.77) | EPHX1CASP2FAAHSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5288905-A | Glycyl urea derivatives as anti-convulsants | G. D. SEARLE & CO. (US) | 1994-02-22 | — | — | US | disclosed |