Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC5 | P28715 | 1/20 | 0.50 |
| ▸ | FEN1 | P39748 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | MYC | P01106 | 1/20 | 0.43 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.42 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.42 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9333335 | 1.00 | ERCC5 (0.50) | ERCC5FEN1HPGDMYCKCNK3 | |
| SCHEMBL9464464 | 0.86 | ERCC5 (0.52) | ERCC5FEN1HPGDMYCGPR52 | |
| SCHEMBL9563141 | 0.82 | ERCC5 (0.49) | ERCC5FEN1HPGDMYCGPR52 | |
| SCHEMBL9359661 | 0.79 | ERCC5 (0.46) | ERCC5FEN1HPGDMYCGPR52 | |
| SCHEMBL6265289 | 0.79 | ERCC5 (0.46) | ERCC5FEN1HPGDMYCGPR52 | |
| SCHEMBL9333311 | 0.79 | KMT2A (0.46) | ERCC5FEN1HPGDMYCGPR52 | |
| SCHEMBL9493449 | 0.79 | KMT2A (0.46) | ERCC5FEN1HPGDMYCGPR52 | |
| SCHEMBL7770355 | 0.79 | ERCC5 (0.46) | ERCC5FEN1HPGDMYCGPR52 | |
| SCHEMBL9359645 | 0.79 | ERCC5 (0.46) | ERCC5FEN1HPGDMYCGPR52 | |
| SCHEMBL7770353 | 0.79 | ERCC5 (0.46) | ERCC5FEN1HPGDMYCGPR52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0594573-A1 | PREPARATION OF PROPENOIC ACID DERIVATIVES | AgrEvo UK Limited (GB) | 1994-05-04 | — | — | EP | disclosed |
| US-5264609-A | Etherification and hydrolysis | SCHERING AGROCHEMICALS LIMITED (GB) | 1993-11-23 | — | — | US | disclosed |
| WO-1991007385-A1 | PREPARATION OF PROPENOIC ACID DERIVATIVES | SCHERING AGROCHEMICALS LIMITED (GB) | 1991-05-30 | — | — | WO | disclosed |