SCHEMBL9563141

SCHEMBL9563141

Cc1ccccc1C(=CC(=O)O)C(=O)O

nearest known ligand 0.58

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ERCC5 P28715 1/20 0.49
FEN1 P39748 1/20 0.49
HPGD P15428 2/20 0.46
KMT2A Q03164 2/20 0.45
MYC P01106 1/20 0.42
GPR52 Q9Y2T5 1/20 0.41
KDM4E B2RXH2 2/20 0.41
ALDH1A1 P00352 1/20 0.41
HSD17B10 Q99714 1/20 0.41
HTT P42858 2/20 0.40
CYP3A4 P08684 1/20 0.40
CYP2C9 P11712 1/20 0.40
TSHR P16473 1/20 0.39
MAPK1 P28482 1/20 0.39
NPC1 O15118 1/20 0.39
RAB9A P51151 1/20 0.39
GAA P10253 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28040521 0.85 RAB9A (0.44) ERCC5FEN1HPGDKMT2AMYC
SCHEMBL9359645 0.85 ERCC5 (0.46) ERCC5FEN1HPGDKMT2AMYC
SCHEMBL9359661 0.85 ERCC5 (0.46) ERCC5FEN1HPGDKMT2AMYC
SCHEMBL9464464 0.84 ERCC5 (0.52) ERCC5FEN1HPGDKMT2AMYC
SCHEMBL9333326 0.82 ERCC5 (0.50) ERCC5FEN1HPGDKMT2AMYC
SCHEMBL9333335 0.82 ERCC5 (0.50) ERCC5FEN1HPGDKMT2AMYC
SCHEMBL20564031 0.79 ERCC5 (0.44) ERCC5FEN1HPGDKMT2AMYC
SCHEMBL20564514 0.79 PPARG (0.43) ERCC5FEN1HPGDKMT2AKDM4E
SCHEMBL17755159 0.78 HPGD (0.47) ERCC5FEN1HPGDKMT2AMYC
SCHEMBL29085634 0.78 HPGD (0.47) ERCC5FEN1HPGDKMT2AMYC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0296878-B1 MODIFIED POLYSILOXANE-COATED SANITARY RUBBER ARTICLE AND PROCESS FOR ITS PRODUCTION DAIKYO GOMU SEIKO LTD. (JP) 1993-09-01 EP disclosed
EP-0296878-A2 Modified polysiloxane-coated sanitary rubber article and process for its production DAIKYO GOMU SEIKO LTD. (JP) 1988-12-28 EP disclosed