Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.36 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.36 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.36 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HTR4 | Q13639 | 3/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | KHK | P50053 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9799578 | 0.88 | EPHX1 (0.35) | EPHX1POLBSMYD3 | |
| SCHEMBL9329935 | 0.81 | KDM4E (0.42) | HPGD | |
| SCHEMBL28291350 | 0.75 | EPHX1 (0.47) | EPHX1POLBGNAI3GNAO1GNAI1 | |
| SCHEMBL28737445 | 0.75 | EPHX1 (0.47) | EPHX1POLBGNAI3GNAO1GNAI1 | |
| SCHEMBL255421 | 0.75 | EPHX1 (0.59) | EPHX1POLBGNAI3GNAO1GNAI1 | |
| SCHEMBL28895020 | 0.73 | EPHX1 (0.57) | EPHX1POLBGNAI3GNAO1GNAI1 | |
| SCHEMBL9799570 | 0.72 | SSTR1 (0.37) | EPHX1POLBGNAI3GNAO1GNAI1 | |
| SCHEMBL1802727 | 0.72 | EPHX1 (0.55) | EPHX1POLBGNAI3GNAO1GNAI1 | |
| SCHEMBL28737429 | 0.71 | EPHX1 (0.42) | EPHX1POLBGNAI3GNAO1GNAI1 | |
| SCHEMBL11007528 | 0.70 | EPHX1 (0.53) | EPHX1POLBGNAI3GNAO1GNAI1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0366004-B1 | Cyclic azaaliphatic compounds with a nitroxy group, process for their preparation and pharmaceutical compositions thereof | BOEHRINGER MANNHEIM GMBH (DE) | 1994-03-30 | — | — | EP | disclosed |
| US-5280031-A | Cyclic azaaliphatic compounds with a nitroxy function, processes for the preparation thereof and pharmaceutical compositions containing them | BOEHRINGER MANNHEIM GMBH (DE) | 1994-01-18 | — | — | US | disclosed |
| EP-0366004-A1 | Cyclic azaaliphatic compounds with a nitroxy group, process for their preparation and pharmaceutical compositions thereof | Roche Diagnostics GmbH (DE) | 1990-05-02 | — | — | EP | disclosed |