Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.43 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP12 | P39900 | 1/20 | 0.42 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9334200 | 0.98 | APP (0.48) | APPCYP3A4CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL9333433 | 0.95 | APP (0.50) | APPCYP3A4CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL9333096 | 0.93 | FFAR1 (0.51) | APPCYP3A4CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL9332966 | 0.93 | FFAR1 (0.51) | APPCYP3A4CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL9335229 | 0.93 | FFAR1 (0.51) | APPCYP3A4CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL9336817 | 0.91 | FFAR1 (0.52) | APPCYP3A4CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL9333484 | 0.89 | APP (0.55) | APPCYP3A4CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL9333042 | 0.87 | LTA4H (0.47) | CYP3A4TSHRMCHR1FFAR1FFAR4 | |
| SCHEMBL14085288 | 0.87 | APP (0.52) | APPCYP3A4CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL8040012 | 0.87 | APP (0.46) | APPCYP3A4CYP2C9CYP2C19ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0377516-B1 | Liquid crystal compounds having high optical anisotropy | CHISSO CORP (JP) | 1994-05-04 | — | — | EP | disclosed |
| US-5154851-A | LIQUID CRYSTAL COMPOUND HAVING LARGE OPTICAL ANISOTROPY VALUE | CHISSO CORPORATION (JP) | 1992-10-13 | — | — | US | disclosed |
| EP-0377516-A2 | Liquid crystal compounds having high optical anisotropy | Chisso Corporation (JP) | 1990-07-11 | — | — | EP | disclosed |