Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | DNM1 | Q05193 | 5/20 | 0.36 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.35 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5702641 | 1.00 | TSHR (0.37) | TSHRLMNADNM1PLA2G1BPLA2G2A | |
| SCHEMBL9333404 | 0.91 | TSHR (0.40) | TSHRDNM1 | |
| SCHEMBL6914555 | 0.81 | PLA2G1B (0.38) | TSHRLMNADNM1PLA2G1BPLA2G2A | |
| SCHEMBL8773721 | 0.78 | TSHR (0.38) | TSHRLMNADNM1PLA2G1BPLA2G2A | |
| SCHEMBL7052656 | 0.78 | TSHR (0.38) | TSHRLMNADNM1PLA2G1BPLA2G2A | |
| SCHEMBL23388971 | 0.75 | TSHR (0.42) | TSHRDNM1 | |
| SCHEMBL13601912 | 0.74 | TSHR (0.46) | TSHRLMNADNM1THRBOPRM1 | |
| SCHEMBL12844942 | 0.74 | TSHR (0.46) | TSHRLMNADNM1THRBOPRM1 | |
| SCHEMBL15211724 | 0.74 | TSHR (0.46) | TSHRLMNADNM1THRBOPRM1 | |
| SCHEMBL366647 | 0.74 | TSHR (0.46) | TSHRLMNADNM1THRBOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0592488-A1 | DIMETHYLAMINO-HYDROXY-ALKAN DIPHOSPHONIC ACIDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | INSTITUTO GENTILI S.P.A. (IT) | 1994-04-20 | — | — | EP | disclosed |
| WO-1993000348-A1 | DIMETHYLAMINO-HYDROXY-ALKAN DIPHOSPHONIC ACIDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ISTITUTO GENTILI S.P.A. (IT) | 1993-01-07 | — | — | WO | disclosed |