Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RHEB | Q15382 | 3/20 | 0.51 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | TYR | P14679 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | TPX2 | Q9ULW0 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TTR | P02766 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31589082 | 1.00 | RHEB (0.51) | RHEBACHETYRUSP2GAA | |
| SCHEMBL25080566 | 0.79 | RHEB (0.50) | RHEBGAAALOX15AURKATPX2 | |
| SCHEMBL21439156 | 0.79 | RHEB (0.50) | RHEBACHEAURKATPX2MTOR | |
| SCHEMBL29506978 | 0.79 | RHEB (0.50) | RHEBACHEAURKATPX2MTOR | |
| SCHEMBL27497556 | 0.79 | HPGD (0.49) | GAANPSR1MEN1KMT2AALDH1A1 | |
| SCHEMBL30733596 | 0.76 | HTT (0.36) | RHEBNPSR1MEN1MAOAMAOB | |
| SCHEMBL28422997 | 0.75 | TYR (0.48) | RHEBTYRUSP2GAAALOX15 | |
| SCHEMBL6862874 | 0.73 | RHEB (0.48) | RHEBUSP2ALOX15MEN1KMT2A | |
| SCHEMBL25254260 | 0.72 | RHEB (0.50) | RHEBTYRAURKATPX2ALDH1A1 | |
| SCHEMBL1958807 | 0.72 | AHR (0.45) | TYRUSP2GAAALOX15RAD51 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0446131-B1 | Keratinous fibres dyeing process with substituted monohydroxy indols and compositions | OREAL (FR) | 1994-05-04 | — | — | EP | claimed |
| EP-0446131-A1 | Keratinous fibres dyeing process with substituted monohydroxy indols and compositions | L'OREAL (FR) | 1991-09-11 | — | — | EP | claimed |
| EP-0446131-B1 | Keratinous fibres dyeing process with substituted monohydroxy indols and compositions | OREAL (FR) | 1994-05-04 | — | — | EP | disclosed |
| EP-0446131-A1 | Keratinous fibres dyeing process with substituted monohydroxy indols and compositions | L'OREAL (FR) | 1991-09-11 | — | — | EP | disclosed |
| US-4229464-A | Aminopropanol substituted indole compounds and compositions for the treatment of cardiac and circulatory diseases | BOEHRINGER MANNHEIM GMBH (DE) | 1980-10-21 | — | — | US | disclosed |
| US-4152446-A | Aminopropanol compounds and compositions for the treatment of cardiac and circulatory diseases | BOEHRINGER MANNHEIM GMBH (DE) | 1979-05-01 | — | — | US | disclosed |
| US-4076829-A | Aminopropanol compounds and compositions for the treatment of cardiac and circulatory diseases | BOEHRINGER MANNHEIM GMBH (DT) | 1978-02-28 | — | — | US | disclosed |