Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 20/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9334162 | 0.93 | LTB4R (0.62) | LTB4R | |
| SCHEMBL9336826 | 0.92 | LTB4R (0.72) | LTB4R | |
| SCHEMBL9373822 | 0.91 | LTB4R (0.60) | LTB4R | |
| SCHEMBL9334167 | 0.88 | LTB4R (0.66) | LTB4R | |
| SCHEMBL9334194 | 0.88 | LTB4R (0.63) | LTB4R | |
| SCHEMBL8862046 | 0.88 | LTB4R (0.68) | LTB4R | |
| SCHEMBL8732073 | 0.87 | LTB4R (0.74) | LTB4R | |
| SCHEMBL9333861 | 0.87 | LTB4R (0.69) | LTB4R | |
| Lithium Ion SCHEMBL9336839 | 0.85 | LTB4R (0.61) | LTB4R | |
| SCHEMBL9335161 | 0.84 | LTB4R (0.59) | LTB4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0604529-A1 | PYRIDINE COMPOUNDS FOR TREATING LEUKOTRIENE-RELATED DISEASES | SMITHKLINE BEECHAM CORPORATION (US) | 1994-07-06 | — | — | EP | disclosed |
| EP-0593464-A1 | BENZOIC ACID DERIVATIVES and their use as LTB4 inhibitors | SMITHKLINE BEECHAM CORPORATION (US) | 1994-04-27 | — | — | EP | disclosed |
| WO-1993006085-A1 | PYRIDINE COMPOUNDS FOR TREATING LEUKOTRIENE-RELATED DISEASES | SMITHKLINE BEECHAM CORPORATION (US) | 1993-04-01 | — | — | WO | disclosed |
| EP-0593464-A4 | BENZOIC ACID DERIVATIVES. | SMITHKLINE BEECHAM CORP (US) | 1993-02-12 | — | — | EP | disclosed |
| WO-1991018601-A1 | BENZOIC ACID DERIVATIVES | SMITHKLINE BEECHAM CORPORATION (US) | 1991-12-12 | — | — | WO | disclosed |