Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.61 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.61 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.61 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.59 |
| ▸ | PTPN7 | P35236 | 5/20 | 0.59 |
| ▸ | RECQL | P46063 | 2/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.59 |
| ▸ | BLM | P54132 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | HMGCR | P04035 | 3/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6137471 | 0.93 | GPR84 (0.73) | GPR84FFAR1FFAR4CAMK2APTPN7 | |
| SCHEMBL4969330 | 0.87 | PTPN7 (0.64) | CAMK2APTPN7RECQLTDP1MAPT | |
| SCHEMBL21682850 | 0.85 | PTPN7 (0.74) | GPR84FFAR1FFAR4PTPN7RECQL | |
| SCHEMBL1936704 | 0.85 | HMGCR (0.69) | GPR84FFAR1FFAR4CAMK2APTPN7 | |
| SCHEMBL10578073 | 0.83 | PTPN7 (0.55) | GPR84FFAR1FFAR4CAMK2APTPN7 | |
| SCHEMBL4972584 | 0.82 | PTPN7 (0.59) | CAMK2APTPN7RECQLTDP1MAPT | |
| SCHEMBL22540045 | 0.82 | PTPN7 (0.78) | GPR84FFAR1FFAR4PTPN7RECQL | |
| SCHEMBL196242 | 0.82 | PTPN7 (0.78) | GPR84FFAR1FFAR4PTPN7RECQL | |
| SCHEMBL196457 | 0.82 | PTPN7 (0.78) | GPR84FFAR1FFAR4PTPN7RECQL | |
| SCHEMBL23121203 | 0.81 | PTPN7 (0.63) | GPR84FFAR1FFAR4CAMK2APTPN7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0364517-B1 | PREVENTION OF PROSTHESIS CALCIFICATION | BIOMEDICAL DESIGN INC (US) | 1994-04-06 | — | — | EP | disclosed |
| EP-0364517-A4 | PREVENTION OF PROSTHESIS CALCIFICATION | — | 1991-01-16 | — | — | EP | disclosed |
| US-4976733-A | USING ALIPHATIC CARBOXYLIC ACID | BIOMEDICAL DESIGN, INC. (US) | 1990-12-11 | — | — | US | disclosed |
| EP-0364517-A1 | PREVENTION OF PROSTHESIS CALCIFICATION. | BIOMEDICAL DESIGN INC (US) | 1990-04-25 | — | — | EP | disclosed |
| WO-1989006945-A1 | PREVENTION OF PROSTHESIS CALCIFICATION | BIOMEDICAL DESIGN, INC. (US) | 1989-08-10 | — | — | WO | disclosed |