Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | ELANE | P08246 | 3/20 | 0.44 |
| ▸ | F2 | P00734 | 2/20 | 0.44 |
| ▸ | PLAU | P00749 | 2/20 | 0.44 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.42 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.42 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9334648 | 0.82 | TSHR (0.46) | SMN1; SMN2MAPTPOLBALDH1A1LMNA | |
| SCHEMBL9331775 | 0.81 | TSHR (0.51) | RAB9ASMN1; SMN2MAPTNPC1POLB | |
| SCHEMBL19208718 | 0.80 | ELANE (0.49) | RAB9ASMN1; SMN2MAPTALDH1A1LMNA | |
| SCHEMBL19208817 | 0.79 | ELANE (0.53) | RAB9ASMN1; SMN2MAPTALDH1A1LMNA | |
| SCHEMBL19208691 | 0.78 | ELANE (0.53) | RAB9ASMN1; SMN2MAPTPOLBALDH1A1 | |
| SCHEMBL11688337 | 0.74 | HSD17B10 (0.38) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL30728062 | 0.72 | CNR2 (0.44) | SMN1; SMN2MAPTPOLBALDH1A1LMNA | |
| SCHEMBL22151034 | 0.72 | CNR2 (0.44) | SMN1; SMN2MAPTPOLBALDH1A1LMNA | |
| SCHEMBL26633067 | 0.72 | CYP1A2 (0.64) | RAB9ASMN1; SMN2MAPTALDH1A1LMNA | |
| SCHEMBL22151026 | 0.72 | MAPT (0.52) | MAPTLMNAELANEMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0448206-B1 | Substituted benzimidazole and indazole derivatives, processes for their preparation and their use as herbicides | ZENECA LTD (GB) | 1994-12-28 | — | — | EP | disclosed |
| US-5306692-A | Herbicidal indazole and benzimidazole compounds | ZENECA LIMITED (GB) | 1994-04-26 | — | — | US | disclosed |
| EP-0448206-A2 | Substituted benzimidazole and indazole derivatives, processes for their preparation and their use as herbicides | ZENECA LIMITED (GB) | 1991-09-25 | — | — | EP | disclosed |