Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.43 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9331775 | 0.86 | TSHR (0.51) | TSHRALDH1A1MAPK1MAPK8SMN1; SMN2 | |
| SCHEMBL9334671 | 0.82 | RAB9A (0.48) | TSHRALDH1A1MAPK1MAPK8SMN1; SMN2 | |
| SCHEMBL19236960 | 0.73 | MEN1 (0.46) | TSHRALDH1A1MAPK1SMN1; SMN2MAPT | |
| SCHEMBL6360534 | 0.73 | HTR2A (0.55) | SLC22A12ESR1 | |
| SCHEMBL9332034 | 0.73 | PLA2G7 (0.38) | TSHRALDH1A1MAPK1MAPK8HTT | |
| SCHEMBL23613366 | 0.72 | TP53 (0.42) | TSHRALDH1A1MAPK8SMN1; SMN2HTT | |
| SCHEMBL19236791 | 0.72 | MEN1 (0.42) | TSHRALDH1A1MAPK1SMN1; SMN2MAPT | |
| SCHEMBL29452022 | 0.71 | TSHR (0.55) | TSHRALDH1A1MAPK1MAPK8SMN1; SMN2 | |
| SCHEMBL19236962 | 0.71 | MEN1 (0.41) | TSHRALDH1A1MAPK1SMN1; SMN2MAPT | |
| SCHEMBL30231463 | 0.71 | GAA (0.52) | TSHRALDH1A1SMN1; SMN2HTTNLRP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0448206-B1 | Substituted benzimidazole and indazole derivatives, processes for their preparation and their use as herbicides | ZENECA LTD (GB) | 1994-12-28 | — | — | EP | disclosed |
| US-5306692-A | Herbicidal indazole and benzimidazole compounds | ZENECA LIMITED (GB) | 1994-04-26 | — | — | US | disclosed |
| EP-0448206-A2 | Substituted benzimidazole and indazole derivatives, processes for their preparation and their use as herbicides | ZENECA LIMITED (GB) | 1991-09-25 | — | — | EP | disclosed |