SCHEMBL933484

SCHEMBL933484

CCCCCCCC/C=C\CCCCCCCC(=O)N(C(=O)CCCCCCCCCCCCCCC)C(CCC(=O)O)C(=O)O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARG P37231 4/20 0.59
PPARD Q03181 4/20 0.59
PPARA Q07869 4/20 0.59
F7 P08709 4/20 0.59
F3 P13726 4/20 0.59
TERT O14746 3/20 0.59
PTPN1 P18031 3/20 0.59
HSD17B10 Q99714 3/20 0.59
FABP4 P15090 3/20 0.59
MAPT P10636 2/20 0.59
BLM P54132 2/20 0.59
LMNA P02545 2/20 0.59
ALOX15 P16050 2/20 0.59
DUSP3 P51452 2/20 0.59
CYP19A1 P11511 2/20 0.59
PTGS1 P23219 2/20 0.59
NR4A2 P43354 2/20 0.59
SIRT6 Q8N6T7 2/20 0.59
PTPN7 P35236 2/20 0.59
TDP1 Q9NUW8 2/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL933485 1.00 PPARG (0.59) PPARGPPARDPPARAF7F3
SCHEMBL933487 1.00 PPARG (0.59) PPARGPPARDPPARAF7F3
SCHEMBL28942411 1.00 PPARG (0.59) PPARGPPARDPPARAF7F3
SCHEMBL933486 1.00 PPARG (0.59) PPARGPPARDPPARAF7F3
SCHEMBL29977843 0.96 PPARG (0.62) PPARGPPARDPPARAF7F3
SCHEMBL29389960 0.91 FFAR4 (0.54) PPARGPPARDPPARAPTPN1HSD17B10
SCHEMBL17179891 0.91 FFAR4 (0.54) PPARGPPARDPPARAPTPN1HSD17B10
SCHEMBL9617729 0.91 FFAR4 (0.54) PPARGPPARDPPARAPTPN1HSD17B10
SCHEMBL29977688 0.91 FFAR4 (0.54) PPARGPPARDPPARAPTPN1HSD17B10
SCHEMBL17179893 0.91 FFAR4 (0.54) PPARGPPARDPPARAPTPN1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11541010-B2 Amphoteric liposomes comprising imino lipids BIONTECH DELIVERY TECHNOLOGIES GMBH (DE) 2023-01-03 US disclosed
US-20200330384-A1 AMPHOTERIC LIPOSOMES COMPRISING IMINO LIPIDS BIONTECH DELIVERY TECHNOLOGIES GMBH (DE) 2020-10-22 US disclosed
EP-2823810-B9 Amphoteric liposomes comprising imino lipids NOVOSOM VERWALTUNGS GMBH (DE) 2019-10-30 EP disclosed
EP-2823810-B1 Amphoteric liposomes comprising imino lipids NOVOSOM VERWALTUNGS GMBH (DE) 2019-03-27 EP disclosed
US-20180338919-A1 AMPHOTERIC LIPOSOMES COMPRISING IMINO LIPIDS NOVOSOM AG (DE) 2018-11-29 US disclosed
US-10039714-B2 Imino compounds for amphoteric liposomes and uses thereof NOVOSOM VERWALTUNGS GMBH (DE) 2018-08-07 US disclosed
EP-2451440-B2 AMPHOTERIC LIPOSOMES COMPRISING IMINO LIPIDS MARINA BIOTECH INC (US) 2018-03-14 EP disclosed
US-20160338957-A1 IMINO COMPOUNDS FOR AMPHOTERIC LIPOSOMES AND USES THEREOF BIONTECH PROTEIN THERAPEUTICS GMBH (DE) 2016-11-24 US disclosed
EP-2823810-A1 Amphoteric liposomes comprising imino lipids Marina Biotech, Inc. (US) 2015-01-14 EP disclosed
EP-2451440-B1 AMPHOTERIC LIPOSOMES COMPRISING IMINO LIPIDS MARINA BIOTECH INC (US) 2014-11-12 EP disclosed
US-20120237589-A1 AMPHOTERIC LIPOSOMES COMPRISING IMINO LIPIDS MARINA BIOTECH, INC. (US) 2012-09-20 US disclosed
EP-2451440-A1 AMPHOTERIC LIPOSOMES COMPRISING IMINO LIPIDS Marina Biotech, Inc. (US) 2012-05-16 EP disclosed
WO-2011003834-A1 AMPHOTERIC LIPOSOMES COMPRISING IMINO LIPIDS MARINA BIOTECH, INC. (US) 2011-01-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160338957-A1 IMINO COMPOUNDS FOR AMPHOTERIC LIPOSOMES AND USES THEREOF IPO8, IPO7, PHOSPHO1 PPARG 3755/4885PPARD 3457/4885PPARA 2917/4885
US-11541010-B2 Amphoteric liposomes comprising imino lipids SGMS1, SGMS2, PHOSPHO1 PPARG 3547/4885PPARD 3364/4885PPARA 2871/4885
US-20120237589-A1 AMPHOTERIC LIPOSOMES COMPRISING IMINO LIPIDS SGMS1, SGMS2, PHOSPHO1 PPARG 3547/4885PPARD 3364/4885PPARA 2871/4885
US-10039714-B2 Imino compounds for amphoteric liposomes and uses thereof IPO8, IPO7, PHOSPHO1 PPARG 3755/4885PPARD 3457/4885PPARA 2917/4885
US-20200330384-A1 AMPHOTERIC LIPOSOMES COMPRISING IMINO LIPIDS SGMS1, SGMS2, PHOSPHO1 PPARG 3547/4885PPARD 3364/4885PPARA 2871/4885
US-20180338919-A1 AMPHOTERIC LIPOSOMES COMPRISING IMINO LIPIDS SGMS1, SGMS2, PHOSPHO1 PPARG 3547/4885PPARD 3364/4885PPARA 2871/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.