Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACAT1 | P24752 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9375757 | 0.86 | ACAT1 (0.69) | ACAT1 | |
| SCHEMBL9335674 | 0.81 | ACAT1 (0.61) | ACAT1 | |
| SCHEMBL9332405 | 0.81 | ACAT1 (0.61) | ACAT1 | |
| SCHEMBL9332852 | 0.81 | ACAT1 (0.73) | ACAT1 | |
| SCHEMBL9425382 | 0.80 | ACAT1 (0.67) | ACAT1 | |
| SCHEMBL9332518 | 0.78 | ACAT1 (0.69) | ACAT1 | |
| SCHEMBL9375747 | 0.76 | ACAT1 (0.73) | ACAT1 | |
| Lecimibide SCHEMBL49619 | 0.75 | ACAT1 (1.00) | ACAT1 | |
| SCHEMBL9370595 | 0.75 | ACAT1 (1.00) | ACAT1 | |
| Lecimibide SCHEMBL30548840 | 0.75 | ACAT1 (1.00) | ACAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5290801-A | Anticholesterol or antilipemic agents | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1994-03-01 | — | — | US | claimed |
| US-5290801-A | Anticholesterol or antilipemic agents | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1994-03-01 | — | — | US | disclosed |