Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A1 | P04798 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TYR | P14679 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | RARB | P10826 | 4/20 | 0.34 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.32 |
| ▸ | CTSL | P07711 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9335289 | 0.99 | TSHR (0.40) | CYP1A1CYP1A2CYP1B1TSHRHSD17B10 | |
| SCHEMBL9337477 | 0.99 | CYP1A1 (0.37) | CYP1A1CYP1A2CYP1B1TSHRHSD17B10 | |
| SCHEMBL9334032 | 0.96 | CYP1A1 (0.40) | CYP1A1CYP1A2CYP1B1TSHRHSD17B10 | |
| SCHEMBL9335264 | 0.90 | CYP1A1 (0.42) | CYP1A1CYP1A2CYP1B1HTTCTSL | |
| SCHEMBL9334205 | 0.89 | CYP1A1 (0.40) | CYP1A1CYP1A2CYP1B1CTSLCTSS | |
| SCHEMBL9333976 | 0.86 | HSD17B10 (0.50) | TSHRHSD17B10MEN1TP53CYP3A4 | |
| SCHEMBL17108393 | 0.85 | TYR (0.43) | TSHRTYRMEN1TP53CYP3A4 | |
| SCHEMBL9333304 | 0.85 | HSD17B10 (0.52) | TSHRHSD17B10MEN1TP53CYP3A4 | |
| SCHEMBL10302708 | 0.84 | CTSL (0.35) | TSHRHSD17B10TYRMEN1TP53 | |
| SCHEMBL10302820 | 0.82 | FFAR1 (0.40) | TSHRHSD17B10TYRMEN1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5328637-A | Electrooptical devices; deformation of aligned phases and supertwisted nematic applications; miscibility, solubility | HOFFMANN-LA ROCHE INC. (US) | 1994-07-12 | — | — | US | disclosed |