SCHEMBL9335604

SCHEMBL9335604

O=C1CCCCN1C(=O)c1cccc(C(=O)N2CCCCC2=O)c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.57
MITF O75030 1/20 0.57
MEN1 O00255 2/20 0.53
KMT2A Q03164 2/20 0.53
CYP1A2 P05177 2/20 0.53
CYP2D6 P10635 2/20 0.53
CYP2C9 P11712 2/20 0.53
CYP2C19 P33261 2/20 0.53
KDM4E B2RXH2 1/20 0.53
MAPT P10636 1/20 0.53
THRB P10828 1/20 0.53
RECQL P46063 1/20 0.53
BLM P54132 1/20 0.53
HPGD P15428 3/20 0.46
ALDH1A1 P00352 2/20 0.46
L3MBTL3 Q96JM7 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
CYP3A4 P08684 1/20 0.46
GAA P10253 1/20 0.44
TSHR P16473 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1824654 0.98 MITF (0.60) SMN1; SMN2MITFMEN1KMT2ACYP1A2
SCHEMBL5182442 0.98 MITF (0.60) SMN1; SMN2MITFMEN1KMT2ACYP1A2
SCHEMBL1823033 0.95 KMT2A (0.58) SMN1; SMN2MITFMEN1KMT2ACYP1A2
SCHEMBL8538473 0.89 MITF (0.51) SMN1; SMN2MITFMEN1KMT2ACYP1A2
SCHEMBL8544392 0.88 MITF (0.53) SMN1; SMN2MITFMEN1KMT2ACYP1A2
SCHEMBL6960124 0.88 SMN1; SMN2 (0.63) SMN1; SMN2MITFMEN1KMT2ACYP1A2
SCHEMBL9874977 0.86 SMN1; SMN2 (0.66) SMN1; SMN2MITFMEN1KMT2ACYP1A2
SCHEMBL151854 0.86 SMN1; SMN2 (0.66) SMN1; SMN2MITFMEN1KMT2ACYP1A2
SCHEMBL8380782 0.86 SMN1; SMN2 (0.66) SMN1; SMN2MITFMEN1KMT2ACYP1A2
SCHEMBL8380683 0.86 SMN1; SMN2 (0.66) SMN1; SMN2MITFMEN1KMT2ACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0366316-B1 Melt-processible aromatic polyamides DU PONT (US) 1994-12-07 EP claimed
US-5066445-A Recovery and melt extrusion of aromatic/aliphatic copolyamides from lactam-plasticized polymer E. I. DU PONT DE NEMOURS AND COMPANY (US) 1991-11-19 US claimed
EP-0366316-A1 Melt-processible aromatic polyamides E.I. DU PONT DE NEMOURS AND COMPANY (US) 1990-05-02 EP claimed
JP-2145620-A None JP disclosed
EP-0366316-B1 Melt-processible aromatic polyamides DU PONT (US) 1994-12-07 EP disclosed
EP-0446870-B1 High strength papers from floc and fibers DU PONT (US) 1994-05-18 EP disclosed
US-5232737-A Heating wire in excess of glass transition temperature of polyamide/polylactam copolymer and melt coating with polymer E. I. DU PONT DE NEMOURS AND COMPANY (US) 1993-08-03 US disclosed
US-5202187-A High temperature/water crazing/and cracking resistance due to copolyamide sheath insulation E. I. DU PONT DE NEMOURS AND COMPANY (US) 1993-04-13 US disclosed
EP-0510219-A1 Coated wire E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-10-28 EP disclosed
US-5136016-A Fibers or films E. I. DU PONT DE NEMOURS AND COMPANY (US) 1992-08-04 US disclosed
US-5126012-A Polyamide-lactam copolymers E. I. DU PONT DE NEMOURS AND COMPANY (US) 1992-06-30 US disclosed
US-5066445-A Recovery and melt extrusion of aromatic/aliphatic copolyamides from lactam-plasticized polymer E. I. DU PONT DE NEMOURS AND COMPANY (US) 1991-11-19 US disclosed
EP-0446870-A1 High strength papers from floc and fibers E.I. DU PONT DE NEMOURS AND COMPANY (US) 1991-09-18 EP disclosed
JP-H02145620-A MELT-PROCESSIBLE AROMATIC POLYAMIDE E I DU PONT DE NEMOURS & CO 1990-06-05 JP disclosed
EP-0366316-A1 Melt-processible aromatic polyamides E.I. DU PONT DE NEMOURS AND COMPANY (US) 1990-05-02 EP disclosed
US-4665410-A THERMOGRAPHY RICOH COMPANY, LTD. (JP) 1987-05-12 US disclosed
US-4663641-A LEUCO DYES; DECOLORIZING AGENTS, PIPERAZINE COMPOUND; AMIDES AND TERTIARY AMINES RICOH COMPANY, LTD. (JP) 1987-05-05 US disclosed
US-4613878-A DECOLORIZING AGENT COMPRISING AROMATIC DIAMIDE OR PIPERAZINE DERIVATIVE, HAVING TWO ACYLAMINO GROUPS RICOH COMPANY, LTD. (JP) 1986-09-23 US disclosed