Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.41 |
| ▸ | SRD5A1 | P18405 | 4/20 | 0.40 |
| ▸ | SRD5A2 | P31213 | 4/20 | 0.40 |
| ▸ | PLA2G4A | P47712 | 2/20 | 0.37 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.35 |
| ▸ | TACR2 | P21452 | 1/20 | 0.35 |
| ▸ | TACR1 | P25103 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.35 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | LTC4S | Q16873 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9335764 | 0.85 | SRD5A1 (0.52) | SRD5A1SRD5A2MCL1HDAC3CREBBP | |
| SCHEMBL9149130 | 0.83 | OXER1 (0.41) | OXER1SRD5A1SRD5A2ALOX5APPTGS2 | |
| SCHEMBL9335665 | 0.81 | SRD5A1 (0.59) | OXER1SRD5A1SRD5A2PLA2G4AALOX5AP | |
| SCHEMBL9148428 | 0.81 | OXER1 (0.46) | OXER1SRD5A1SRD5A2ALOX5APTP53 | |
| SCHEMBL9153196 | 0.80 | OXER1 (0.47) | OXER1SRD5A1SRD5A2ALOX5APMCL1 | |
| SCHEMBL9152733 | 0.80 | AKR1C3 (0.42) | SRD5A1SRD5A2ALOX5APPTGS2CREBBP | |
| SCHEMBL9156276 | 0.79 | OXER1 (0.48) | OXER1SRD5A1SRD5A2ALOX5APMCL1 | |
| SCHEMBL9149623 | 0.78 | OXER1 (0.46) | OXER1SRD5A1SRD5A2ALOX5APMCL1 | |
| SCHEMBL8792776 | 0.77 | SRD5A1 (0.61) | SRD5A1SRD5A2MCL1CREBBP | |
| SCHEMBL9334438 | 0.76 | CNR1 (0.46) | SRD5A1SRD5A2MCL1HDAC3CREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5312829-A | Testosterone 5alpha-reductase inhibitors | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-05-17 | — | — | US | disclosed |
| US-5212320-A | Enzyme inhibitors | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-05-18 | — | — | US | disclosed |
| EP-0458207-A2 | Indole derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-11-27 | — | — | EP | disclosed |