Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.41 |
| ▸ | SRD5A1 | P18405 | 4/20 | 0.40 |
| ▸ | SRD5A2 | P31213 | 4/20 | 0.40 |
| ▸ | ALOX5AP | P20292 | 3/20 | 0.39 |
| ▸ | HTR6 | P50406 | 2/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | HTR1D | P28221 | 1/20 | 0.39 |
| ▸ | HTR1B | P28222 | 1/20 | 0.39 |
| ▸ | HTR1F | P30939 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.36 |
| ▸ | PLK1 | P53350 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | LTC4S | Q16873 | 1/20 | 0.35 |
| ▸ | IL6ST | P40189 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9148428 | 0.96 | OXER1 (0.46) | OXER1SRD5A1SRD5A2ALOX5APHTR6 | |
| SCHEMBL9153196 | 0.95 | OXER1 (0.47) | OXER1SRD5A1SRD5A2ALOX5APHTR6 | |
| SCHEMBL9156276 | 0.94 | OXER1 (0.48) | OXER1SRD5A1SRD5A2ALOX5APHTR6 | |
| SCHEMBL9152733 | 0.92 | AKR1C3 (0.42) | SRD5A1SRD5A2ALOX5APHTR6HTR1A | |
| SCHEMBL9149623 | 0.89 | OXER1 (0.46) | OXER1SRD5A1SRD5A2ALOX5APHTR6 | |
| SCHEMBL9429193 | 0.87 | OXER1 (0.47) | OXER1SRD5A1SRD5A2ALOX5APHTR6 | |
| SCHEMBL9153124 | 0.86 | PLA2G4A (0.38) | OXER1SRD5A1SRD5A2ALOX5APHTR6 | |
| SCHEMBL9335671 | 0.83 | OXER1 (0.41) | OXER1SRD5A1SRD5A2ALOX5APCREBBP | |
| SCHEMBL9150612 | 0.83 | OXER1 (0.48) | OXER1HTR6HTR1AHTR1DHTR1B | |
| SCHEMBL9369456 | 0.81 | OXER1 (0.49) | OXER1SRD5A1SRD5A2HTR6HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0516849-B1 | INDOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO (JP) | 1995-01-25 | — | — | EP | disclosed |
| US-5283251-A | Testosterone 5a-reductase inhibitors | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-02-01 | — | — | US | disclosed |
| EP-0516849-A1 | INDOLE DERIVATIVES. | FUJISAWA PHARMACEUTICAL CO (JP) | 1992-12-09 | — | — | EP | disclosed |
| WO-1991013060-A1 | INDOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-09-05 | — | — | WO | disclosed |