Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A1 | P18405 | 5/20 | 0.75 |
| ▸ | SRD5A2 | P31213 | 5/20 | 0.75 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.48 |
| ▸ | TERT | O14746 | 4/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.39 |
| ▸ | CDC25A | P30304 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9334434 | 0.90 | SRD5A1 (0.61) | SRD5A1SRD5A2HDAC3HDAC1HDAC8 | |
| SCHEMBL29633452 | 0.86 | SRD5A1 (1.00) | SRD5A1SRD5A2 | |
| SCHEMBL3504489 | 0.86 | SRD5A1 (1.00) | SRD5A1SRD5A2 | |
| SCHEMBL9335665 | 0.85 | SRD5A1 (0.59) | SRD5A1SRD5A2HDAC3 | |
| Hydrochloric Acid SCHEMBL8793978 | 0.85 | SRD5A1 (0.98) | SRD5A1SRD5A2 | |
| SCHEMBL9386762 | 0.84 | SRD5A1 (0.91) | SRD5A1SRD5A2 | |
| SCHEMBL8793523 | 0.83 | SRD5A1 (0.95) | SRD5A1SRD5A2 | |
| SCHEMBL8792770 | 0.82 | SRD5A1 (0.90) | SRD5A1SRD5A2 | |
| N-Phenylbenzamide SCHEMBL6762152 | 0.82 | SRD5A1 (0.91) | SRD5A1SRD5A2PTGDR2 | |
| SCHEMBL9335764 | 0.81 | SRD5A1 (0.52) | SRD5A1SRD5A2HDAC3TERTMCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5312829-A | Testosterone 5alpha-reductase inhibitors | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-05-17 | — | — | US | disclosed |
| US-5212320-A | Enzyme inhibitors | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-05-18 | — | — | US | disclosed |
| EP-0458207-A2 | Indole derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-11-27 | — | — | EP | disclosed |