SCHEMBL29633452

SCHEMBL29633452

CC(C)Cc1ccc(C(Nc2cccc(C(=O)c3cn(CCCC(=O)O)c4ccccc34)c2)c2ccc(CC(C)C)cc2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
SRD5A1 P18405 6/20 1.00
SRD5A2 P31213 6/20 1.00
CNR1 P21554 3/20 0.49
CNR2 P34972 3/20 0.49
MAPT P10636 2/20 0.43
POLB P06746 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
KMT2A Q03164 1/20 0.41
CREBBP Q92793 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3504489 1.00 SRD5A1 (1.00) SRD5A1SRD5A2CNR1CNR2MAPT
Hydrochloric Acid SCHEMBL8793978 0.99 SRD5A1 (0.98) SRD5A1SRD5A2CNR1CNR2MAPT
SCHEMBL8793523 0.97 SRD5A1 (0.95) SRD5A1SRD5A2CNR1CNR2MAPT
N-Phenylbenzamide SCHEMBL6762152 0.95 SRD5A1 (0.91) SRD5A1SRD5A2CNR1CNR2MAPT
SCHEMBL9386762 0.95 SRD5A1 (0.91) SRD5A1SRD5A2CNR1CNR2
SCHEMBL8792770 0.95 SRD5A1 (0.90) SRD5A1SRD5A2CNR1CNR2MAPT
SCHEMBL8793385 0.93 SRD5A1 (0.88) SRD5A1SRD5A2CNR1CNR2MAPT
SCHEMBL9336300 0.93 SRD5A1 (0.86) SRD5A1SRD5A2CNR1CNR2MAPT
SCHEMBL9337867 0.91 SRD5A1 (0.84) SRD5A1SRD5A2CNR1CNR2MAPT
SCHEMBL8792545 0.91 SRD5A1 (0.83) SRD5A1SRD5A2CNR1CNR2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3220942-B1 COMPOSITIONS COMPRISING LOW DOSE DESMOPRESSIN IN COMBINATION WITH AN ALPHA-ADRENERGIC RECEPTOR ANTAGONIST SERENITY PHARMACEUTICALS LLC (US) 2022-04-27 EP claimed
US-20250295634-A1 USE OF ANTIANDROGENS TO TREAT SEPSIS RHODE ISLAND HOSPITAL 2025-09-25 US disclosed
EP-3220942-B1 COMPOSITIONS COMPRISING LOW DOSE DESMOPRESSIN IN COMBINATION WITH AN ALPHA-ADRENERGIC RECEPTOR ANTAGONIST SERENITY PHARMACEUTICALS LLC (US) 2022-04-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250295634-A1 USE OF ANTIANDROGENS TO TREAT SEPSIS SHBG, AR, HSD17B11 SRD5A1 12/4885SRD5A2 11/4885CNR1 3258/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.