Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9335724 | 0.90 | NR4A2 (0.51) | RAB9AMAPTTSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL10950578 | 0.87 | MAPT (0.61) | RAB9ANPC1MAPTGAATSHR | |
| SCHEMBL9339326 | 0.87 | MAPT (0.57) | RAB9ANPC1MAPTGAATSHR | |
| SCHEMBL9339195 | 0.85 | RAB9A (0.50) | RAB9ANPC1MAPTGAATSHR | |
| SCHEMBL9339257 | 0.81 | RAB9A (0.51) | RAB9ANPC1MAPTGAATSHR | |
| SCHEMBL10951141 | 0.81 | GAA (0.63) | RAB9ANPC1MAPTGAATSHR | |
| SCHEMBL9335517 | 0.80 | MAPT (0.62) | RAB9ANPC1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL9339054 | 0.80 | GAA (0.53) | RAB9ANPC1MAPTGAATSHR | |
| SCHEMBL9337330 | 0.79 | MAPT (0.60) | RAB9ANPC1MAPTALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL9337253 | 0.78 | MAPT (0.59) | RAB9ANPC1MAPTLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0394440-B1 | PHENYLCARBOXYLIC ACID DERIVATIVES | OTSUKA PHARMA CO LTD (JP) | 1994-05-11 | — | — | EP | disclosed |
| US-4999378-A | Antilipemic, anticholesterol, antidiabetic, treatment of atherosclerosis and obesity | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1991-03-12 | — | — | US | disclosed |
| EP-0394440-A1 | PHENYLCARBOXYLIC ACID DERIVATIVES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1990-10-31 | — | — | EP | disclosed |