Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 6/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | PTPRG | P23470 | 1/20 | 0.34 |
| ▸ | ICMT | O60725 | 1/20 | 0.34 |
| ▸ | GMNN | O75496 | 1/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9336203 | 1.00 | KMT2A (0.38) | KMT2AL3MBTL1POLBHSD17B10SMN1; SMN2 | |
| SCHEMBL9336042 | 0.92 | KMT2A (0.36) | KMT2AL3MBTL1POLBHSD17B10SMN1; SMN2 | |
| SCHEMBL9336046 | 0.92 | KMT2A (0.36) | KMT2AL3MBTL1POLBHSD17B10SMN1; SMN2 | |
| SCHEMBL9692513 | 0.89 | RAB9A (0.38) | KMT2AL3MBTL1POLBHSD17B10SMN1; SMN2 | |
| SCHEMBL9692521 | 0.89 | RAB9A (0.38) | KMT2AL3MBTL1POLBHSD17B10SMN1; SMN2 | |
| SCHEMBL9333403 | 0.85 | PPARG (0.39) | KMT2AL3MBTL1POLBHSD17B10SMN1; SMN2 | |
| SCHEMBL9333392 | 0.85 | PPARG (0.39) | KMT2AL3MBTL1POLBHSD17B10SMN1; SMN2 | |
| SCHEMBL8637704 | 0.84 | KMT2A (0.53) | KMT2AL3MBTL1POLBHSD17B10SMN1; SMN2 | |
| SCHEMBL8960857 | 0.84 | KMT2A (0.53) | KMT2AL3MBTL1POLBHSD17B10SMN1; SMN2 | |
| SCHEMBL9335893 | 0.84 | PTPRG (0.41) | KMT2AL3MBTL1POLBHSD17B10SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0594573-A1 | PREPARATION OF PROPENOIC ACID DERIVATIVES | AgrEvo UK Limited (GB) | 1994-05-04 | — | — | EP | disclosed |
| US-5264609-A | Etherification and hydrolysis | SCHERING AGROCHEMICALS LIMITED (GB) | 1993-11-23 | — | — | US | disclosed |
| WO-1991007385-A1 | PREPARATION OF PROPENOIC ACID DERIVATIVES | SCHERING AGROCHEMICALS LIMITED (GB) | 1991-05-30 | — | — | WO | disclosed |