⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13093828 | 1.00 | — | — | |
| SCHEMBL12398463 | 0.73 | — | — | |
| SCHEMBL238049 | 0.71 | — | — | |
| SCHEMBL2390538 | 0.71 | — | — | |
| SCHEMBL3860874 | 0.71 | — | — | |
| SCHEMBL10580480 | 0.69 | — | — | |
| SCHEMBL269235 | 0.67 | — | — | |
| SCHEMBL17265960 | 0.67 | — | — | |
| SCHEMBL9336453 | 0.67 | — | — | |
| SCHEMBL13971386 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0319482-B1 | Novel substituted propane phosphinic acid compounds | CIBA GEIGY AG (CH) | 1994-05-18 | — | — | EP | disclosed |
| US-5300679-A | Antagonists to 4-aminobutyric acid | CIBA-GEIGY CORPORATION (US) | 1994-04-05 | — | — | US | disclosed |
| US-5190933-A | Treatment of cognitive and memory disorders | CIBA-GEIGY CORPORATION (US) | 1993-03-02 | — | — | US | disclosed |
| US-5064819-A | Antidepressants, anxiolytic agents, GABA antagonists | CIBA-GEIGY CORPORATION (US) | 1991-11-12 | — | — | US | disclosed |
| US-5051524-A | Treatment of a phosphinic acid with an anhydrous protic medium | CIBA-GEIGY CORPORATION (US) | 1991-09-24 | — | — | US | disclosed |
| EP-0425570-A1 | OXIDATION HYDROLYSIS OF IODOALKANES | EASTMAN KODAK COMPANY (US) | 1991-05-08 | — | — | EP | disclosed |
| US-5013863-A | Learning enhancement | CIBA-GEIGY CORPORATION (US) | 1991-05-07 | — | — | US | disclosed |
| WO-1990000520-A1 | OXIDATION HYDROLYSIS OF IODOALKANES | EASTMAN KODAK COMPANY (US) | 1990-01-25 | — | — | WO | disclosed |
| EP-0351338-A1 | Oxidation hydrolysis of iodoalkanes | EASTMAN CHEMICAL COMPANY (US) | 1990-01-17 | — | — | EP | disclosed |
| US-4863710-A | Oxidation hydrolysis of iodoalkanes | EASTMAN KODAK COMPANY (US) | 1989-09-05 | — | — | US | disclosed |
| EP-0319479-A2 | Substituted propane-phosphinic acid compounds | CIBA-GEIGY AG (CH) | 1989-06-07 | — | — | EP | disclosed |
| EP-0319482-A2 | Novel substituted propane phosphinic acid compounds | CIBA-GEIGY AG (CH) | 1989-06-07 | — | — | EP | disclosed |