Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10730287 | 0.89 | POLB (0.43) | PKMPOLBNPC1RAB9AL3MBTL1 | |
| SCHEMBL10729049 | 0.88 | CYP19A1 (0.47) | POLBNPC1RAB9AL3MBTL1KCNA5 | |
| SCHEMBL10724078 | 0.87 | CYP19A1 (0.43) | NPC1RAB9AL3MBTL1KCNA5CYP11B1 | |
| SCHEMBL10724819 | 0.87 | CYP19A1 (0.52) | NPC1RAB9AL3MBTL1CYP3A4CYP19A1 | |
| SCHEMBL10730234 | 0.86 | POLB (0.44) | PKMPOLBNPC1RAB9AL3MBTL1 | |
| SCHEMBL12870553 | 0.85 | CYP19A1 (0.41) | PKMPOLBNPC1RAB9AL3MBTL1 | |
| SCHEMBL933961 | 0.84 | POLB (0.43) | PKMPOLBNPC1RAB9AL3MBTL1 | |
| SCHEMBL10730253 | 0.82 | CYP3A4 (0.42) | NPC1RAB9AL3MBTL1KCNA5CYP11B1 | |
| SCHEMBL10724842 | 0.82 | CYP19A1 (0.46) | KCNA5LMNACYP3A4CYP19A1 | |
| SCHEMBL10726693 | 0.81 | KCNA5 (0.46) | PKMPOLBNPC1RAB9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140357649-A1 | Phenyl(oxy/thio)alkanol Derivatives | BAYER CROPSCIENCE AG (DE) | 2014-12-04 | — | — | US | claimed |
| EP-2451784-A1 | PHENYL(OXY/THIO)ALKANOL DERIVATIVES | Bayer CropScience AG (DE) | 2012-05-16 | — | — | EP | claimed |
| US-20110039865-A1 | Phenyl(oxy/thio)alkanol Derivatives | BAYER CROPSCIENCE AG (DE) | 2011-02-17 | — | — | US | claimed |
| WO-2011003527-A1 | PHENYL(OXY/THIO)ALKANOL DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2011-01-13 | — | — | WO | claimed |
| US-9321732-B2 | Phenyl(oxy/thio)alkanol derivatives | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-04-26 | — | — | US | disclosed |
| US-9051277-B2 | Phenyl(oxy/thio)alkanol derivatives | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-06-09 | — | — | US | disclosed |
| US-20140357649-A1 | Phenyl(oxy/thio)alkanol Derivatives | BAYER CROPSCIENCE AG (DE) | 2014-12-04 | — | — | US | disclosed |
| EP-2451784-A1 | PHENYL(OXY/THIO)ALKANOL DERIVATIVES | Bayer CropScience AG (DE) | 2012-05-16 | — | — | EP | disclosed |
| US-20110039865-A1 | Phenyl(oxy/thio)alkanol Derivatives | BAYER CROPSCIENCE AG (DE) | 2011-02-17 | — | — | US | disclosed |
| WO-2011003527-A1 | PHENYL(OXY/THIO)ALKANOL DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2011-01-13 | — | — | WO | disclosed |
| US-4677128-A | (Arylthio)-pyridylalkanols and their use as fungicides | RHONE-POULENC AGROCHIMIE (FR) | 1987-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140357649-A1 | Phenyl(oxy/thio)alkanol Derivatives | MYB, ALKBH3, OSBP | PKM 1529/4885POLB 1600/4885NPC1 2853/4885 |
| US-20110039865-A1 | Phenyl(oxy/thio)alkanol Derivatives | MYB, ALKBH3, OSBP | PKM 1529/4885POLB 1600/4885NPC1 2853/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.