SCHEMBL9337041

SCHEMBL9337041

CCC[C@H]1CC[C@H](CC[C@H]2CC[C@H](c3ccc(C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)cc3)CC2)CC1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.49
LMNA P02545 1/20 0.49
MAPT P10636 1/20 0.49
CYP2C9 P11712 3/20 0.48
MEN1 O00255 1/20 0.46
MAPK1 P28482 1/20 0.46
KMT2A Q03164 1/20 0.46
ESR2 Q92731 6/20 0.38
HTR2C P28335 2/20 0.36
ESR1 P03372 4/20 0.33
CYP3A4 P08684 2/20 0.33
IDO1 P14902 2/20 0.32
CNR2 P34972 2/20 0.32
SPHK1 Q9NYA1 1/20 0.31
DRD2 P14416 1/20 0.31
OPRM1 P35372 1/20 0.31
OPRK1 P41145 1/20 0.31
OPRL1 P41146 1/20 0.31
TDO2 P48775 1/20 0.31
CYP2D6 P10635 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9337026 1.00 ALDH1A1 (0.49) ALDH1A1LMNAMAPTCYP2C9MEN1
SCHEMBL9338739 0.95 ALDH1A1 (0.47) ALDH1A1LMNAMAPTCYP2C9MEN1
SCHEMBL9341004 0.95 ALDH1A1 (0.47) ALDH1A1LMNAMAPTCYP2C9MEN1
SCHEMBL11277880 0.95 ALDH1A1 (0.47) ALDH1A1LMNAMAPTCYP2C9MEN1
SCHEMBL9341001 0.95 ALDH1A1 (0.47) ALDH1A1LMNAMAPTCYP2C9MEN1
SCHEMBL9338732 0.95 ALDH1A1 (0.47) ALDH1A1LMNAMAPTCYP2C9MEN1
SCHEMBL11285016 0.93 ALDH1A1 (0.48) ALDH1A1LMNAMAPTCYP2C9MEN1
SCHEMBL9336480 0.92 MAPT (0.41) ALDH1A1LMNAMAPTCYP2C9MEN1
SCHEMBL9336894 0.92 MAPT (0.41) ALDH1A1LMNAMAPTCYP2C9MEN1
SCHEMBL9337341 0.92 ALDH1A1 (0.40) ALDH1A1LMNAMAPTCYP2C9MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5348677-A Electro-optical liquid crystal display element MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1994-09-20 US disclosed
US-5196140-A ELECTRO-OPTICAL LIQUID CRYSTAL DISPLAY ELEMENT MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1993-03-23 US disclosed