Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.53 |
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.47 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9337738 | 0.90 | PPARG (0.56) | PPARGACHEAGTR1AGTR2 | |
| SCHEMBL9336755 | 0.89 | PPARG (0.58) | PPARGACHEAGTR1AGTR2 | |
| SCHEMBL9337491 | 0.88 | PPARG (0.52) | PPARGACHE | |
| SCHEMBL9339238 | 0.87 | PPARG (0.53) | PPARGACHE | |
| SCHEMBL9337685 | 0.87 | PPARG (0.53) | PPARGACHE | |
| SCHEMBL9337403 | 0.87 | PPARG (0.53) | PPARGACHE | |
| SCHEMBL9337841 | 0.86 | PPARG (0.50) | PPARGACHEAGTR1AGTR2 | |
| SCHEMBL9337063 | 0.86 | PPARG (0.52) | PPARGACHE | |
| SCHEMBL9340726 | 0.86 | PPARG (0.52) | PPARGACHEAGTR1 | |
| SCHEMBL9339313 | 0.85 | AGTR1 (0.53) | PPARGACHEAGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5332750-A | Treatment of hypertension, aldosteronism, cardiac insufficienc y | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1994-07-26 | — | — | US | disclosed |