Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.47 |
| ▸ | PPARG | P37231 | 6/20 | 0.38 |
| ▸ | PPARA | Q07869 | 6/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | TGM2 | P21980 | 1/20 | 0.36 |
| ▸ | AKT1 | P31749 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | PDE6D | O43924 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2769911 | 0.89 | GAA (0.46) | THRBPPARAGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL1830713 | 0.88 | THRB (0.45) | THRBPPARGPPARAMTNR1AMTNR1B | |
| SCHEMBL17792519 | 0.86 | PPARG (0.48) | THRBPPARGPPARA | |
| SCHEMBL218320 | 0.86 | THRB (0.46) | THRBPPARGPPARAMTNR1AMTNR1B | |
| Acrylic Acid SCHEMBL29368977 | 0.85 | THRB (0.44) | THRBPPARGPPARAMTNR1AMTNR1B | |
| SCHEMBL5355849 | 0.84 | THRB (0.53) | THRBPPARGPPARAMTNR1AMTNR1B | |
| Ethylene Glycol SCHEMBL517990 | 0.84 | THRB (0.49) | THRBPPARGPPARAMTNR1AMTNR1B | |
| SCHEMBL3053163 | 0.83 | THRB (0.44) | THRBPPARGPPARAMTNR1AMTNR1B | |
| SCHEMBL183158 | 0.83 | THRB (0.44) | THRBPPARGPPARAMTNR1AMTNR1B | |
| SCHEMBL9491739 | 0.81 | THRB (0.43) | THRBPPARGPPARATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113286560-A | Orthodontic articles and methods of making and post-treating the same | 3M创新有限公司 | 2021-08-20 | — | — | CN | disclosed |
| CN-112367959-A | Orthodontic articles comprising cured free-radically polymerizable compositions having improved strength in aqueous environments | 3M创新有限公司 | 2021-02-12 | — | — | CN | disclosed |
| CN-111868125-A | Photopolymerizable compositions, articles, and methods comprising polypropylene oxide components | 3M创新有限公司 | 2020-10-30 | — | — | CN | disclosed |
| CN-111615377-A | Orthodontic articles comprising cured free-radically polymerizable compositions containing polymers or macromolecules with photoinitiating groups | 3M创新有限公司 | 2020-09-01 | — | — | CN | disclosed |
| EP-0377927-B1 | The use of azole accelerators in anaerobic compositions | THREE BOND CO LTD (JP) | 1994-05-04 | — | — | EP | disclosed |
| EP-0377927-A1 | The use of azole accelerators in anaerobic compositions | THREE BOND CO., LTD. (JP) | 1990-07-18 | — | — | EP | disclosed |