Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.43 |
| ▸ | MEF2D | Q14814 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 3/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.40 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.39 |
| ▸ | TLR4 | O00206 | 1/20 | 0.38 |
| ▸ | TLR2 | O60603 | 1/20 | 0.38 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | RXRB | P28702 | 1/20 | 0.38 |
| ▸ | EP300 | Q09472 | 1/20 | 0.38 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9342447 | 0.92 | ALDH1A1 (0.45) | KDM4EALDH1A1SMN1; SMN2MAOBMAOA | |
| SCHEMBL9342546 | 0.91 | TLR4 (0.50) | KDM4EALDH1A1SMN1; SMN2MAOBPKM | |
| SCHEMBL9337876 | 0.90 | CYSLTR2 (0.50) | KDM4EALDH1A1SMN1; SMN2PKMCYSLTR2 | |
| SCHEMBL9342093 | 0.89 | CYSLTR2 (0.52) | KDM4EALDH1A1SMN1; SMN2CYSLTR2TLR4 | |
| SCHEMBL9342494 | 0.89 | CYSLTR2 (0.52) | KDM4EALDH1A1SMN1; SMN2CYSLTR2TLR4 | |
| SCHEMBL9337348 | 0.89 | CYSLTR2 (0.52) | KDM4EALDH1A1SMN1; SMN2CYSLTR2TLR4 | |
| SCHEMBL9338292 | 0.89 | CYSLTR2 (0.52) | KDM4EALDH1A1SMN1; SMN2CYSLTR2TLR4 | |
| SCHEMBL9339752 | 0.89 | CYSLTR2 (0.52) | KDM4EALDH1A1SMN1; SMN2CYSLTR2TLR4 | |
| SCHEMBL9338557 | 0.89 | CYSLTR2 (0.52) | KDM4EALDH1A1SMN1; SMN2CYSLTR2TLR4 | |
| SCHEMBL9338411 | 0.89 | CYSLTR2 (0.52) | KDM4EALDH1A1SMN1; SMN2CYSLTR2TLR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0328668-B1 | NONLINEAR OPTICAL MATERIAL | NIPPON OILS & FATS CO LTD (JP) | 1994-05-25 | — | — | EP | disclosed |
| US-5045239-A | Chalcone derivative | NIPPON OIL AND FATS CO., LTD. (JP) | 1991-09-03 | — | — | US | disclosed |
| EP-0328668-A1 | NONLINEAR OPTICAL MATERIAL | NIPPON OIL AND FATS COMPANY, LIMITED (JP) | 1989-08-23 | — | — | EP | disclosed |