Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.38 |
| ▸ | PTPRZ1 | P23471 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.33 |
| ▸ | KCNK10 | P57789 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9342882 | 0.86 | SMN1; SMN2 (0.41) | SMN1; SMN2MAPTHPGDMGLLHSD17B10 | |
| SCHEMBL9430863 | 0.82 | SMN1; SMN2 (0.38) | SMN1; SMN2MAPTHPGDMGLLHSD17B10 | |
| SCHEMBL10641762 | 0.82 | SMN1; SMN2 (0.38) | SMN1; SMN2MAPTHPGDMGLLHSD17B10 | |
| SCHEMBL25118323 | 0.82 | SMN1; SMN2 (0.38) | SMN1; SMN2MAPTHPGDMGLLHSD17B10 | |
| SCHEMBL10641263 | 0.82 | SMN1; SMN2 (0.38) | SMN1; SMN2MAPTHPGDMGLLHSD17B10 | |
| SCHEMBL777056 | 0.80 | ALDH1A1 (0.56) | SMN1; SMN2MAPTHPGDMGLLHSD17B10 | |
| SCHEMBL10489143 | 0.80 | SMN1; SMN2 (0.45) | SMN1; SMN2MAPTHPGDMGLLHSD17B10 | |
| SCHEMBL28674848 | 0.80 | SMN1; SMN2 (0.45) | SMN1; SMN2MAPTHPGDMGLLHSD17B10 | |
| SCHEMBL431548 | 0.78 | MAPT (0.43) | SMN1; SMN2MAPTHPGDMGLLHSD17B10 | |
| Water SCHEMBL28356277 | 0.78 | ALDH1A1 (0.54) | SMN1; SMN2MAPTHPGDMGLLHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1032201-C | Process for preparing perhaloalkylthioethers | RHONE POULENC AGROCHIMIE (FR) | 1996-07-03 | — | — | CN | disclosed |
| EP-0374061-B1 | Process for the preparation of perhalogen alkyl thio ethers | RHONE POULENC AGROCHIMIE (FR) | 1994-06-15 | — | — | EP | disclosed |
| US-5283337-A | Reacting reducing agent, disulfide, perhaloalkyl halide | RHONE-POULENC AGROCHIMIE (FR) | 1994-02-01 | — | — | US | disclosed |
| US-5082945-A | Reducing agent, perfluoroalkyl halide, disulfide | RHONE-POULENC AGROCHIMIE (FR) | 1992-01-21 | — | — | US | disclosed |
| EP-0374061-A1 | Process for the preparation of perhalogen alkyl thio ethers | RHONE-POULENC AGROCHIMIE (FR) | 1990-06-20 | — | — | EP | disclosed |
| EP-0117780-B1 | PROCESS FOR THE PREPARATION OF PERHALOGENOALKYLTHIO ETHERS | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1986-03-05 | — | — | EP | disclosed |
| US-4552984-A | SULFONYLATION IN PRESENCE OF BORON TRIFLUORIDE, HYDROGEN FLUORIDE | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1985-11-12 | — | — | US | disclosed |
| EP-0092627-B1 | PROCESS FOR THE PREPARATION OF DI- OR TRIFLUOROMETHOXYPHENYL KETONES OR OF DI- OR TRIFLUOROMETHYLTHIOPHENYL KETONES | RHONE-POULENC CHIMIE (FR) | 1985-05-29 | — | — | EP | disclosed |
| EP-0085265-B1 | PROCESS FOR THE PREPARATION OF ALPHA,ALPHA-DIFLUOROALKOXY OR ALPHA,ALPHA-DIFLUOROALKYLTHIOPHENYL KETONES | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1985-05-22 | — | — | EP | disclosed |
| EP-0084743-B1 | PROCESS FOR THE PREPARATION OF ALPHA, ALPHA-DIFLUOROALKOXY OR ALPHA, ALPHADIFLUOROALKYLTHIOPHENYL SULFONES | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1984-11-21 | — | — | EP | disclosed |
| EP-0117780-A1 | Process for the preparation of perhalogenoalkylthio ethers | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1984-09-05 | — | — | EP | disclosed |
| US-4446078-A | REACTING A POLYHALOALKOXY- OR POLYHALOALKYLTHIOBENZENE WITH A CARBOXYLIC DERIVATIVE, BORON TRIFLUORIDE | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1984-05-01 | — | — | US | disclosed |
| US-4438043-A | Process for preparation of di- or trifluoromethoxyphenyl ketones or di- or trifluoromethylthiophenyl ketones | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1984-03-20 | — | — | US | disclosed |
| EP-0092627-A1 | Process for the preparation of di- or trifluoromethoxyphenyl ketones or of di- or trifluoromethylthiophenyl ketones | RHONE-POULENC CHIMIE (FR) | 1983-11-02 | — | — | EP | disclosed |
| EP-0085265-A1 | Process for the preparation of alpha,alpha-difluoroalkoxy or alpha,alpha-difluoroalkylthiophenyl ketones | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1983-08-10 | — | — | EP | disclosed |
| EP-0084743-A1 | Process for the preparation of alpha, alpha-difluoroalkoxy or alpha, alphadifluoroalkylthiophenyl sulfones | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1983-08-03 | — | — | EP | disclosed |