Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.77 |
| ▸ | MAOB | P27338 | 8/20 | 0.69 |
| ▸ | MAOA | P21397 | 6/20 | 0.69 |
| ▸ | POLB | P06746 | 1/20 | 0.69 |
| ▸ | RAB9A | P51151 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.66 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.66 |
| ▸ | HPGD | P15428 | 2/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.66 |
| ▸ | LMNA | P02545 | 3/20 | 0.64 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | PKM | P14618 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | ATM | Q13315 | 2/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.56 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28727204 | 1.00 | MAPT (0.77) | MAPTMAOBMAOAPOLBRAB9A | |
| SCHEMBL9561400 | 1.00 | MAPT (0.77) | MAPTMAOBMAOAPOLBRAB9A | |
| SCHEMBL11994844 | 0.93 | MAOB (0.77) | MAPTMAOBMAOAPOLBRAB9A | |
| SCHEMBL28850948 | 0.93 | MAOB (0.77) | MAPTMAOBMAOAPOLBRAB9A | |
| SCHEMBL23082622 | 0.89 | MAOB (0.71) | MAPTMAOBMAOAPOLBRAB9A | |
| 4,4'-Dimethylchalcone SCHEMBL979560 | 0.88 | MAPT (1.00) | MAPTMAOBMAOAPOLBRAB9A | |
| 4,4'-Dimethylchalcone SCHEMBL979559 | 0.88 | MAPT (1.00) | MAPTMAOBMAOAPOLBRAB9A | |
| SCHEMBL8965047 | 0.87 | F3 (0.74) | MAPTMAOBMAOAPOLBRAB9A | |
| SCHEMBL15631515 | 0.87 | MAPT (0.77) | MAPTMAOBMAOAPOLBRAB9A | |
| SCHEMBL8965046 | 0.87 | F3 (0.74) | MAPTMAOBMAOAPOLBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5257179-A | — | — | None | — | — | JP | disclosed |
| EP-0328668-B1 | NONLINEAR OPTICAL MATERIAL | NIPPON OILS & FATS CO LTD (JP) | 1994-05-25 | — | — | EP | disclosed |
| JP-H05257179-A | ORGANIC NONLINEAR OPTICAL MATERIAL | MITSUBISHI KASEI CORP | 1993-10-08 | — | — | JP | disclosed |
| US-5045239-A | Chalcone derivative | NIPPON OIL AND FATS CO., LTD. (JP) | 1991-09-03 | — | — | US | disclosed |
| EP-0328669-A1 | CHALCONE DERIVATIVE COMPOUNDS | NIPPON OIL AND FATS COMPANY, LIMITED (JP) | 1989-08-23 | — | — | EP | disclosed |