Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 1.00 |
| ▸ | MAOB | P27338 | 7/20 | 0.86 |
| ▸ | MAOA | P21397 | 4/20 | 0.86 |
| ▸ | POLB | P06746 | 1/20 | 0.86 |
| ▸ | RAB9A | P51151 | 1/20 | 0.86 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.82 |
| ▸ | HPGD | P15428 | 3/20 | 0.82 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.82 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.82 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.75 |
| ▸ | HTT | P42858 | 3/20 | 0.72 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.72 |
| ▸ | PKM | P14618 | 2/20 | 0.72 |
| ▸ | ATM | Q13315 | 2/20 | 0.72 |
| ▸ | LMNA | P02545 | 2/20 | 0.72 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.72 |
| ▸ | MEN1 | O00255 | 1/20 | 0.72 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 4,4'-Dimethylchalcone SCHEMBL979559 | 1.00 | MAPT (1.00) | MAPTMAOBMAOAPOLBRAB9A | |
| SCHEMBL22098902 | 0.94 | MAPT (0.89) | MAPTMAOBMAOAPOLBRAB9A | |
| SCHEMBL22099225 | 0.94 | MAPT (0.89) | MAPTMAOBMAOAPOLBRAB9A | |
| SCHEMBL548040 | 0.93 | MAPT (1.00) | MAPTMAOBMAOAPOLBRAB9A | |
| SCHEMBL8965069 | 0.93 | MAPT (1.00) | MAPTMAOBMAOAPOLBRAB9A | |
| SCHEMBL25194931 | 0.93 | MAPT (0.86) | MAPTMAOBMAOAPOLBRAB9A | |
| SCHEMBL10497491 | 0.93 | MAPT (0.86) | MAPTMAOBMAOAPOLBRAB9A | |
| SCHEMBL548041 | 0.93 | MAPT (1.00) | MAPTMAOBMAOAPOLBRAB9A | |
| SCHEMBL10299698 | 0.93 | MAPT (0.86) | MAPTMAOBMAOAPOLBRAB9A | |
| SCHEMBL8480925 | 0.93 | MAPT (0.86) | MAPTMAOBMAOAPOLBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 153 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115400106-B | Application of natural compound and composition thereof in removing aging cells | 清华大学 | 2024-01-19 | — | — | CN | disclosed |
| CN-115141621-A | Oil-based fracturing fluid, multi-stage fracturing method and method for online monitoring productivity of reservoir intervals | 中国石油化工股份有限公司 | 2022-10-04 | — | — | CN | disclosed |
| CN-111892559-B | Application of chiral TADDOL ligand and rare earth metal amide in combined catalysis of asymmetric reaction | 苏州大学 | 2022-04-12 | — | — | CN | disclosed |
| CN-107922830-B | Electrochromic compounds and optical articles containing them | 依视路国际公司 | 2021-08-20 | — | — | CN | disclosed |
| CN-111892559-A | Application of chiral TADDOL ligand and rare earth metal amide in combined catalysis of asymmetric reaction | 苏州大学 | 2020-11-06 | — | — | CN | disclosed |
| EP-3351980-B1 | INFRARED-RAY REFLECTIVE MEMBER | DAINIPPON PRINTING CO LTD (JP) | 2020-09-30 | — | — | EP | disclosed |
| US-10563120-B2 | Electrochromic compounds and optical articles containing them | ESSILOR INTERNATIONAL (FR) | 2020-02-18 | — | — | US | disclosed |
| EP-3115433-B1 | ELECTROCHROMIC COMPOUNDS AND OPTICAL ARTICLES CONTAINING THEM | ESSILOR INT (FR) | 2018-10-03 | — | — | EP | disclosed |
| EP-3351980-A1 | INFRARED-RAY REFLECTIVE MEMBER | Dai Nippon Printing Co., Ltd. (JP) | 2018-07-25 | — | — | EP | disclosed |
| US-20180194995-A1 | ELECTROCHROMIC COMPOUNDS AND OPTICAL ARTICLES CONTAINING THEM | ESSILOR INTERNATIONAL (FR) | 2018-07-12 | — | — | US | disclosed |
| US-7158299-B2 | Projection screen and projection system comprising the same | DAI NIPPON PRINTING CO., LTD. (JP) | 2007-01-02 | — | — | US | disclosed |
| US-20050148599-A1 | Chalcone and its analogs as agents for the inhibition of angiogenesis and related disease states | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. | 2005-07-07 | — | — | US | disclosed |
| US-6906105-B2 | Chalcone and its analogs as agents for the inhibition of angiogenesis and related disease states | BOWEN J PHILLIP (US) | 2005-06-14 | — | — | US | disclosed |
| US-6462075-B1 | USE OF CHALCONE AND ITS DERIVATIVES AS ANTITUMOR/ANTICANCER AGENTS AND TO TREAT A NUMBER OF CONDITIONS OR DISEASE STATES IN WHICH ANGIOGENESIS IS A FACTOR INCLUDING PSORIASIS, ACNE, ROSACEA, WARTS, ECZEMA, HEMANGIOMAS AND LYMPHANGIOGENESIS | THE UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. | 2002-10-08 | — | — | US | disclosed |
| EP-0693502-B1 | Catalyst component for the polymerization of alpha-olefins and a process for preparing alpha-olefin polymers with use of same | MITSUBISHI CHEM CORP (JP) | 1997-11-05 | — | — | EP | disclosed |
| US-5594081-A | METALLOCENES | MITSUBISHI CHEMICAL CORPORATION (JP) | 1997-01-14 | — | — | US | disclosed |
| EP-0693502-A1 | Catalyst component for the polymerization of alpha-olefins and a process for preparing alpha-olefin polymers with use of same | MITSUBISHI CHEMICAL CORPORATION (JP) | 1996-01-24 | — | — | EP | disclosed |
| EP-0328668-B1 | NONLINEAR OPTICAL MATERIAL | NIPPON OILS & FATS CO LTD (JP) | 1994-05-25 | — | — | EP | disclosed |
| US-5045239-A | Chalcone derivative | NIPPON OIL AND FATS CO., LTD. (JP) | 1991-09-03 | — | — | US | disclosed |
| EP-0328668-A1 | NONLINEAR OPTICAL MATERIAL | NIPPON OIL AND FATS COMPANY, LIMITED (JP) | 1989-08-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180194995-A1 | ELECTROCHROMIC COMPOUNDS AND OPTICAL ARTICLES CONTAINING THEM | EYA2, EYA3, ALDH1A2 | MAPT 133/4885MAOB 927/4885MAOA 1177/4885 |
| US-10563120-B2 | Electrochromic compounds and optical articles containing them | EYA2, EYA3, ALDH1A2 | MAPT 133/4885MAOB 927/4885MAOA 1177/4885 |
| US-20050148599-A1 | Chalcone and its analogs as agents for the inhibition of angiogenesis and related disease states | FLT1, VEGFA, FLT4 | MAPT 341/4885MAOB 1509/4885MAOA 1059/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.