Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | PPARA | Q07869 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.46 |
| ▸ | CTSG | P08311 | 1/20 | 0.46 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.46 |
| ▸ | CMA1 | P23946 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27946160 | 1.00 | NPC1 (0.53) | NPC1MEN1KMT2ASMN1; SMN2RAB9A | |
| SCHEMBL26199701 | 1.00 | NPC1 (0.53) | NPC1MEN1KMT2ASMN1; SMN2RAB9A | |
| SCHEMBL9338571 | 1.00 | NPC1 (0.53) | NPC1MEN1KMT2ASMN1; SMN2RAB9A | |
| SCHEMBL9465077 | 0.89 | POLB (0.57) | NPC1MEN1KMT2ASMN1; SMN2RAB9A | |
| SCHEMBL9465072 | 0.89 | POLB (0.57) | NPC1MEN1KMT2ASMN1; SMN2RAB9A | |
| SCHEMBL160178 | 0.86 | GAA (0.54) | KMT2ASMN1; SMN2RAB9AALDH1A1PPARG | |
| SCHEMBL17283030 | 0.86 | GAA (0.54) | KMT2ASMN1; SMN2RAB9AALDH1A1PPARG | |
| SCHEMBL1109091 | 0.86 | GAA (0.54) | KMT2ASMN1; SMN2RAB9AALDH1A1PPARG | |
| SCHEMBL225433 | 0.86 | GAA (0.54) | KMT2ASMN1; SMN2RAB9AALDH1A1PPARG | |
| SCHEMBL6231982 | 0.86 | GAA (0.54) | KMT2ASMN1; SMN2RAB9AALDH1A1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0322236-B1 | Catalytic process for preparing optically active threonine | TAKASAGO PERFUMERY CO LTD (JP) | 1994-05-04 | — | — | EP | disclosed |
| US-4906773-A | Process for preparing optically active threonine | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1990-03-06 | — | — | US | disclosed |
| EP-0322236-A2 | Catalytic process for preparing optically active threonine | Takasago International Corporation (JP) | 1989-06-28 | — | — | EP | disclosed |