Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 5/20 | 0.66 |
| ▸ | THRB | P10828 | 5/20 | 0.66 |
| ▸ | MAPT | P10636 | 2/20 | 0.65 |
| ▸ | ATG4B | Q9Y4P1 | 12/20 | 0.64 |
| ▸ | PLA2G1B | P04054 | 10/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.64 |
| ▸ | RECQL | P46063 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | MAOA | P21397 | 1/20 | 0.58 |
| ▸ | MAOB | P27338 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9338015 | 1.00 | THRA (0.66) | THRATHRBMAPTATG4BPLA2G1B | |
| SCHEMBL9342084 | 1.00 | THRA (0.66) | THRATHRBMAPTATG4BPLA2G1B | |
| SCHEMBL9338132 | 1.00 | THRA (0.66) | THRATHRBMAPTATG4BPLA2G1B | |
| SCHEMBL9342489 | 1.00 | THRA (0.66) | THRATHRBMAPTATG4BPLA2G1B | |
| SCHEMBL9342252 | 1.00 | THRA (0.66) | THRATHRBMAPTATG4BPLA2G1B | |
| SCHEMBL9342522 | 1.00 | THRA (0.66) | THRATHRBMAPTATG4BPLA2G1B | |
| SCHEMBL9338749 | 1.00 | THRA (0.66) | THRATHRBMAPTATG4BPLA2G1B | |
| SCHEMBL18762730 | 0.99 | MAPT (0.67) | THRATHRBMAPTATG4BPLA2G1B | |
| SCHEMBL18762727 | 0.99 | MAPT (0.67) | THRATHRBMAPTATG4BPLA2G1B | |
| SCHEMBL9337982 | 0.94 | MAPT (0.69) | THRATHRBMAPTATG4BPLA2G1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0328668-B1 | NONLINEAR OPTICAL MATERIAL | NIPPON OILS & FATS CO LTD (JP) | 1994-05-25 | — | — | EP | disclosed |
| US-5045239-A | Chalcone derivative | NIPPON OIL AND FATS CO., LTD. (JP) | 1991-09-03 | — | — | US | disclosed |
| EP-0328668-A1 | NONLINEAR OPTICAL MATERIAL | NIPPON OIL AND FATS COMPANY, LIMITED (JP) | 1989-08-23 | — | — | EP | disclosed |
| EP-0328669-A1 | CHALCONE DERIVATIVE COMPOUNDS | NIPPON OIL AND FATS COMPANY, LIMITED (JP) | 1989-08-23 | — | — | EP | disclosed |