Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.55 |
| ▸ | ADAM17 | P78536 | 12/20 | 0.49 |
| ▸ | MMP13 | P45452 | 5/20 | 0.47 |
| ▸ | MMP9 | P14780 | 4/20 | 0.47 |
| ▸ | MMP1 | P03956 | 3/20 | 0.47 |
| ▸ | MMP2 | P08253 | 3/20 | 0.46 |
| ▸ | MMP8 | P22894 | 2/20 | 0.46 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.46 |
| ▸ | MMP7 | P09237 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTR1D | P28221 | 1/20 | 0.42 |
| ▸ | HTR1B | P28222 | 1/20 | 0.42 |
| ▸ | MMP14 | P50281 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6265267 | 1.00 | KCNH2 (0.55) | KCNH2ADAM17MMP13MMP9MMP1 | |
| SCHEMBL15274643 | 0.88 | ADAM17 (0.58) | ADAM17MMP13MMP9MMP1MMP2 | |
| SCHEMBL9808291 | 0.85 | KCNH2 (0.57) | KCNH2KCNA3LTA4HCA12CA1 | |
| SCHEMBL9757323 | 0.82 | NPC1 (0.48) | ADAM17MMP13MMP9MMP1MMP2 | |
| SCHEMBL1790840 | 0.81 | KCNH2 (0.53) | KCNH2KCNA3LTA4HCA12CA1 | |
| SCHEMBL30992194 | 0.80 | ADAM17 (0.45) | KCNH2ADAM17MMP13MMP9MMP1 | |
| SCHEMBL2908938 | 0.80 | ADAM17 (0.51) | KCNH2ADAM17MMP13MMP9MMP1 | |
| SCHEMBL19543265 | 0.80 | NQO1 (0.61) | ADAM17MMP13MMP9MMP1MMP2 | |
| SCHEMBL14085300 | 0.80 | KCNH2 (0.53) | KCNH2KCNA3LTA4HCA12CA1 | |
| SCHEMBL3632790 | 0.80 | TDP1 (0.56) | ADAM17MMP13MMP9MMP1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0317265-B1 | Novel imidate insecticides | ZENECA INC (US) | 1994-06-01 | — | — | EP | claimed |
| US-5070097-A | MITICIDES | ICI AMERICAS INC. (US) | 1991-12-03 | — | — | US | claimed |
| US-5045566-A | Phenyl or naphthyl substituted | ICI AMERICAS INC. (US) | 1991-09-03 | — | — | US | claimed |
| US-4994473-A | For plants | ICI AMERICAS INC. (US) | 1991-02-19 | — | — | US | claimed |
| EP-0317265-A2 | Novel imidate insecticides | ZENECA INC. (US) | 1989-05-24 | — | — | EP | claimed |
| EP-0317259-A2 | Heterocyclic insecticides | ICI AMERICAS INC. (US) | 1989-05-24 | — | — | EP | claimed |
| JP-2000172-A | — | — | None | — | — | JP | disclosed |
| EP-0317265-B1 | Novel imidate insecticides | ZENECA INC (US) | 1994-06-01 | — | — | EP | disclosed |
| US-5089623-A | Certain imidate insecticides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-02-18 | — | — | US | disclosed |
| US-5089623-A | Certain imidate insecticides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-02-18 | — | — | US | disclosed |
| US-5070210-A | Novel ketenimines as intermediates for insecticides | ICI AMERICAS INC. (US) | 1991-12-03 | — | — | US | disclosed |
| US-5070210-A | Novel ketenimines as intermediates for insecticides | ICI AMERICAS INC. (US) | 1991-12-03 | — | — | US | disclosed |
| US-5070097-A | MITICIDES | ICI AMERICAS INC. (US) | 1991-12-03 | — | — | US | disclosed |
| US-4994473-A | For plants | ICI AMERICAS INC. (US) | 1991-02-19 | — | — | US | disclosed |
| EP-0317259-A3 | HETEROCYCLIC INSECTICIDES | ICI AMERICAS INC. (US) | 1990-10-17 | — | — | EP | disclosed |
| JP-H02172-A | HETEROCYCLIC INSECTICIDE | ICI AMERICAS INC | 1990-01-05 | — | — | JP | disclosed |
| EP-0317265-A2 | Novel imidate insecticides | ZENECA INC. (US) | 1989-05-24 | — | — | EP | disclosed |
| EP-0317265-A2 | Novel imidate insecticides | ZENECA INC. (US) | 1989-05-24 | — | — | EP | disclosed |
| EP-0317259-A2 | Heterocyclic insecticides | ICI AMERICAS INC. (US) | 1989-05-24 | — | — | EP | disclosed |
| EP-0317259-A2 | Heterocyclic insecticides | ICI AMERICAS INC. (US) | 1989-05-24 | — | — | EP | disclosed |