Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | RAB9A | P51151 | 5/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.42 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.41 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.41 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9335600 | 0.90 | NR4A2 (0.53) | RAB9ANPC1MEN1KMT2ANR4A2 | |
| SCHEMBL9339202 | 0.84 | MAPT (0.52) | MAPTRAB9ANPC1KDM4ETDP1 | |
| SCHEMBL9339040 | 0.82 | MAPT (0.55) | MAPTRAB9ANPC1KDM4ETDP1 | |
| Hydrochloric Acid SCHEMBL9339518 | 0.81 | RAB9A (0.53) | MAPTRAB9ANPC1TDP1L3MBTL1 | |
| SCHEMBL6020046 | 0.80 | MAPT (0.68) | MAPTRAB9ANPC1KDM4ETDP1 | |
| SCHEMBL25686475 | 0.79 | MAPT (0.75) | MAPTRAB9ANPC1KDM4ETDP1 | |
| SCHEMBL9339039 | 0.79 | MAPT (0.51) | MAPTRAB9ANPC1KDM4ETDP1 | |
| SCHEMBL9337508 | 0.78 | MAPT (0.57) | MAPTRAB9ANPC1KDM4EL3MBTL1 | |
| SCHEMBL9337596 | 0.78 | MAPT (0.50) | MAPTRAB9ANPC1KDM4ETDP1 | |
| SCHEMBL9335742 | 0.78 | MAPT (0.50) | MAPTRAB9ANPC1KDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0394440-B1 | PHENYLCARBOXYLIC ACID DERIVATIVES | OTSUKA PHARMA CO LTD (JP) | 1994-05-11 | — | — | EP | disclosed |
| US-4999378-A | Antilipemic, anticholesterol, antidiabetic, treatment of atherosclerosis and obesity | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1991-03-12 | — | — | US | disclosed |
| EP-0394440-A1 | PHENYLCARBOXYLIC ACID DERIVATIVES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1990-10-31 | — | — | EP | disclosed |