Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | GAA | P10253 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | CRHBP | P24387 | 1/20 | 0.49 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1304941 | 0.87 | GAA (0.48) | MAPTGAAALDH1A1MEN1KMT2A | |
| SCHEMBL27882210 | 0.85 | MAPT (0.56) | MAPTALDH1A1KMT2ACRHBPCRHR2 | |
| SCHEMBL9337406 | 0.84 | MAPT (0.62) | MAPTGAAALDH1A1MEN1KMT2A | |
| SCHEMBL23827416 | 0.83 | MEN1 (0.56) | MAPTGAAALDH1A1MEN1KMT2A | |
| SCHEMBL23827415 | 0.83 | MEN1 (0.56) | MAPTGAAALDH1A1MEN1KMT2A | |
| SCHEMBL1496777 | 0.82 | GAA (0.63) | MAPTGAAALDH1A1MEN1KMT2A | |
| SCHEMBL3045885 | 0.82 | MAPT (0.68) | MAPTGAAALDH1A1MEN1KMT2A | |
| SCHEMBL10643494 | 0.82 | GAA (0.58) | MAPTGAAALDH1A1MAOBCRHBP | |
| Ammonia Solution, Strong SCHEMBL11662415 | 0.81 | GAA (0.62) | MAPTGAAALDH1A1MEN1KMT2A | |
| SCHEMBL9112581 | 0.81 | ALDH1A1 (0.56) | MAPTGAAALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113979907-A | Cyclohexane-1, 3-dione compound and application thereof | 郑州恒诚仪器耗材有限公司 | 2022-01-28 | — | — | CN | disclosed |
| CN-111205208-B | Cyclohexane-1, 3-diketone compound and synthetic method and application thereof | 郑州恒诚仪器耗材有限公司 | 2021-12-17 | — | — | CN | disclosed |
| CN-111205208-A | Cyclohexane-1, 3-diketone compound and synthetic method and application thereof | 郑州手性药物研究院有限公司 | 2020-05-29 | — | — | CN | disclosed |
| EP-0394440-B1 | PHENYLCARBOXYLIC ACID DERIVATIVES | OTSUKA PHARMA CO LTD (JP) | 1994-05-11 | — | — | EP | disclosed |
| US-4999378-A | Antilipemic, anticholesterol, antidiabetic, treatment of atherosclerosis and obesity | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1991-03-12 | — | — | US | disclosed |
| EP-0394440-A1 | PHENYLCARBOXYLIC ACID DERIVATIVES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1990-10-31 | — | — | EP | disclosed |