Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.65 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | CASP3 | P42574 | 1/20 | 0.56 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.56 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.56 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.56 |
| ▸ | CES2 | O00748 | 1/20 | 0.53 |
| ▸ | CES1 | P23141 | 1/20 | 0.53 |
| ▸ | MMP13 | P45452 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | PARP1 | P09874 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.48 |
| ▸ | ACR | P10323 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4216005 | 0.85 | KMT2A (0.54) | KMT2AMEN1CES2CES1 | |
| SCHEMBL9339370 | 0.82 | SMN1; SMN2 (0.53) | KMT2AMEN1CES2CES1SMN1; SMN2 | |
| SCHEMBL17743 | 0.81 | TAAR1 (0.60) | — | |
| SCHEMBL29351751 | 0.81 | TAAR1 (0.60) | — | |
| SCHEMBL11758692 | 0.80 | ESR1 (0.74) | ESR1ESR2KMT2AMEN1CASP3 | |
| SCHEMBL28519972 | 0.80 | ESR1 (0.73) | ESR1ESR2KMT2AMEN1CASP3 | |
| SCHEMBL27744379 | 0.80 | ESR1 (0.73) | ESR1ESR2KMT2AMEN1CASP3 | |
| SCHEMBL11028366 | 0.79 | TAAR1 (0.58) | — | |
| SCHEMBL9339316 | 0.79 | ESR1 (0.72) | ESR1ESR2KMT2AMEN1CASP3 | |
| SCHEMBL28818160 | 0.79 | ESR1 (1.00) | ESR1ESR2KMT2AMEN1CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5288871-A | Modify balance between rates of bone resorption and formation | AMERICAN HOME PRODUCTS CORPORATION (US) | 1994-02-22 | — | — | US | disclosed |