Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 10/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.46 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.46 |
| ▸ | NSD2 | O96028 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9339370 | 0.90 | SMN1; SMN2 (0.53) | KMT2ATDP1MEN1MAPTALDH1A1 | |
| SCHEMBL9339348 | 0.87 | KMT2A (0.53) | KMT2ATDP1MEN1MAPTALDH1A1 | |
| SCHEMBL29995417 | 0.85 | KMT2A (0.56) | KMT2ATDP1MEN1MAPTALDH1A1 | |
| SCHEMBL9511333 | 0.85 | KMT2A (0.56) | KMT2ATDP1MEN1MAPTALDH1A1 | |
| SCHEMBL18324277 | 0.85 | KMT2A (0.56) | KMT2ATDP1MEN1MAPTALDH1A1 | |
| SCHEMBL27773271 | 0.85 | KMT2A (0.56) | KMT2ATDP1MEN1MAPTALDH1A1 | |
| SCHEMBL9339409 | 0.85 | ESR1 (0.65) | KMT2AMEN1CES2CES1 | |
| SCHEMBL28944513 | 0.84 | KMT2A (0.54) | KMT2ATDP1MEN1MAPTALDH1A1 | |
| SCHEMBL27447227 | 0.84 | LOXL2 (0.55) | KMT2ATDP1MEN1MAPTALDH1A1 | |
| SCHEMBL27628085 | 0.83 | CYP4F2 (0.58) | KMT2ATDP1MEN1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090005436-A1 | Substituted Aminoalkyl- and Amidoalkyl-Benzopyran Derivatives | NEWRON PHARMACEUTICALS S.P.A. (IT) | 2009-01-01 | — | — | US | disclosed |
| EP-1863784-A1 | SUBSTITUTED AMINOALKYL- AND AMIDOALKYL-BENZOPYRAN DERIVATIVES | Newron Pharmaceuticals S.p.A. (IT) | 2007-12-12 | — | — | EP | disclosed |
| WO-2006102958-A1 | SUBSTITUTED AMINOALKYL- AND AMIDOALKYL-BENZOPYRAN DERIVATIVES | NEWRON PHARMACEUTICALS S.P.A. (IT) | 2006-10-05 | — | — | WO | disclosed |
| CN-1338934-A | Mono-acyloxy aralkyl neuronuscular relaxants | NEWLAXANT L L C (US) | 2002-03-06 | — | — | CN | disclosed |
| US-5288871-A | Modify balance between rates of bone resorption and formation | AMERICAN HOME PRODUCTS CORPORATION (US) | 1994-02-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090005436-A1 | Substituted Aminoalkyl- and Amidoalkyl-Benzopyran Derivatives | MAOB, MAOA, AOC3 | KMT2A 1823/4885TDP1 818/4885MEN1 2876/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.