SCHEMBL933945

SCHEMBL933945

CCCCC(=O)NCc1ccc(OC)cc1

nearest known ligand 0.89

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 2/20 0.76
CNR2 P34972 1/20 0.74
ALDH1A1 P00352 3/20 0.70
HPGD P15428 2/20 0.68
EPHX2 P34913 3/20 0.63
HDAC3 O15379 1/20 0.62
HDAC4 P56524 1/20 0.62
HDAC1 Q13547 1/20 0.62
HDAC7 Q8WUI4 1/20 0.62
HDAC2 Q92769 1/20 0.62
HDAC10 Q969S8 1/20 0.62
HDAC11 Q96DB2 1/20 0.62
HDAC8 Q9BY41 1/20 0.62
HDAC6 Q9UBN7 1/20 0.62
HDAC9 Q9UKV0 1/20 0.62
HDAC5 Q9UQL6 1/20 0.62
TRPV1 Q8NER1 1/20 0.62
STS P08842 1/20 0.61
NPC1 O15118 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20399568 0.96 CNR1 (0.70) CNR1CNR2ALDH1A1HPGDEPHX2
SCHEMBL16762031 0.95 CNR1 (0.82) CNR1CNR2ALDH1A1EPHX2STS
SCHEMBL12215285 0.94 CNR1 (0.85) CNR1CNR2ALDH1A1HPGDEPHX2
SCHEMBL12127405 0.90 CNR1 (0.67) CNR1CNR2ALDH1A1NPC1
SCHEMBL11873499 0.88 ALDH1A1 (0.70) CNR1CNR2ALDH1A1TRPV1NPC1
SCHEMBL18255425 0.87 CNR1 (1.00) CNR1CNR2HPGDEPHX2TRPV1
SCHEMBL23000078 0.86 ALDH1A1 (0.68) CNR1CNR2ALDH1A1HPGDTRPV1
SCHEMBL17009241 0.86 ALDH1A1 (0.68) CNR1CNR2ALDH1A1TRPV1NPC1
SCHEMBL8269670 0.86 HPGD (0.66) CNR1CNR2ALDH1A1HPGDEPHX2
SCHEMBL28820388 0.86 ALDH1A1 (0.68) CNR1CNR2ALDH1A1EPHX2TRPV1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109896918-B Unsaturated carbonyl compound and preparation method and application thereof 北京大学深圳研究生院 2022-05-06 CN disclosed
WO-2011006935-A2 TETRAZOLE DERIVATIVES MERCK SERONO S.A. (CH) 2011-01-20 WO disclosed