Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 5/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.66 |
| ▸ | MEN1 | O00255 | 3/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.66 |
| ▸ | CA12 | O43570 | 1/20 | 0.65 |
| ▸ | CA1 | P00915 | 1/20 | 0.65 |
| ▸ | CA2 | P00918 | 1/20 | 0.65 |
| ▸ | CA4 | P22748 | 1/20 | 0.65 |
| ▸ | CA6 | P23280 | 1/20 | 0.65 |
| ▸ | CA7 | P43166 | 1/20 | 0.65 |
| ▸ | TPMT | P51580 | 1/20 | 0.65 |
| ▸ | CA9 | Q16790 | 1/20 | 0.65 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.65 |
| ▸ | POLB | P06746 | 3/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 3/20 | 0.60 |
| ▸ | RAB9A | P51151 | 3/20 | 0.60 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.60 |
| ▸ | PIM1 | P11309 | 1/20 | 0.60 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11162884 | 0.89 | PKM (0.82) | PKMALDH1A1MEN1KMT2ACA12 | |
| SCHEMBL4141962 | 0.84 | MEN1 (0.89) | PKMALDH1A1MEN1KMT2APOLB | |
| SCHEMBL6349892 | 0.83 | ATM (0.68) | PKMALDH1A1MEN1KMT2APOLB | |
| Hydrochloric Acid SCHEMBL9638131 | 0.83 | MEN1 (0.86) | PKMALDH1A1MEN1KMT2APOLB | |
| SCHEMBL9337489 | 0.83 | MEN1 (0.64) | PKMALDH1A1MEN1KMT2APOLB | |
| SCHEMBL9587189 | 0.81 | NPC1 (0.73) | PKMALDH1A1MEN1KMT2ACA1 | |
| SCHEMBL17664663 | 0.80 | MEN1 (0.72) | PKMALDH1A1MEN1KMT2APOLB | |
| Veratric Acid SCHEMBL29386353 | 0.80 | CA12 (1.00) | PKMALDH1A1CA12CA1CA2 | |
| Veratric Acid SCHEMBL976032 | 0.80 | CA12 (1.00) | PKMALDH1A1CA12CA1CA2 | |
| Veratric Acid SCHEMBL114848 | 0.80 | CA12 (1.00) | PKMALDH1A1CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0460083-B1 | DERIVATIVES OF N-PHENYLBENZAMIDE WITH ANTI-ULCER AND ANTI-ALLERGY ACTIVITY AND A METHOD FOR THEIR PREPARATION | ROTTA RESEARCH LAB (IT) | 1994-06-08 | — | — | EP | disclosed |
| US-5232937-A | Cytoprotective agents, antisecretory agents, antagonist | ROTTA RESEARCH LABORATORIUM SPA. (IT) | 1993-08-03 | — | — | US | disclosed |
| WO-1990009989-A1 | DERIVATIVES OF N-PHENYLBENZAMIDE WITH ANTI-ULCER AND ANTI-ALLERGY ACTIVITY AND A METHOD FOR THEIR PREPARATION | ROTTA RESEARCH LABORATORIUM S.P.A. (IT) | 1990-09-07 | — | — | WO | disclosed |