Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 4/20 | 0.51 |
| ▸ | CNR2 | P34972 | 9/20 | 0.50 |
| ▸ | CNR1 | P21554 | 6/20 | 0.50 |
| ▸ | PLK1 | P53350 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.45 |
| ▸ | HRH2 | P25021 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9340471 | 0.83 | CNR2 (0.70) | CNR2CNR1PLK1MEN1KMT2A | |
| SCHEMBL548607 | 0.83 | CNR2 (0.70) | CNR2CNR1PLK1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL2035939 | 0.82 | CNR2 (0.68) | CNR2CNR1PLK1MEN1KMT2A | |
| SCHEMBL12643110 | 0.81 | CNR2 (0.69) | CNR2CNR1PLK1 | |
| Hydrochloric Acid SCHEMBL2041733 | 0.80 | CNR2 (0.67) | CNR2CNR1PLK1 | |
| SCHEMBL4234228 | 0.79 | CNR2 (0.50) | CNR2CNR1PLK1ENPP2 | |
| SCHEMBL10086144 | 0.78 | CNR2 (0.49) | CNR2CNR1PLK1LMNA | |
| SCHEMBL25084322 | 0.76 | IDO1 (0.52) | IDO1CNR2CNR1MEN1LMNA | |
| SCHEMBL31323947 | 0.76 | LMNA (0.64) | IDO1CNR2CNR1MEN1LMNA | |
| SCHEMBL9540544 | 0.75 | PLK1 (0.66) | CNR2CNR1PLK1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0600955-A1 | 5-HT4 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1994-06-15 | — | — | EP | disclosed |
| WO-1993003725-A1 | 5-HT4 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1993-03-04 | — | — | WO | disclosed |