Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.43 |
| ▸ | RELA | Q04206 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 7/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | RARB | P10826 | 3/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | ACR | P10323 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9340816 | 1.00 | TSHR (0.44) | TSHRSMN1; SMN2NPC1LMNANFKB1 | |
| SCHEMBL9340850 | 1.00 | TSHR (0.44) | TSHRSMN1; SMN2NPC1LMNANFKB1 | |
| SCHEMBL9340651 | 1.00 | TSHR (0.44) | TSHRSMN1; SMN2NPC1LMNANFKB1 | |
| SCHEMBL9340823 | 1.00 | TSHR (0.44) | TSHRSMN1; SMN2NPC1LMNANFKB1 | |
| SCHEMBL9340843 | 1.00 | TSHR (0.44) | TSHRSMN1; SMN2NPC1LMNANFKB1 | |
| SCHEMBL14802211 | 1.00 | TSHR (0.44) | TSHRSMN1; SMN2NPC1LMNANFKB1 | |
| SCHEMBL10476833 | 0.92 | SMN1; SMN2 (0.43) | SMN1; SMN2NPC1LMNANFKB1NFKB2 | |
| SCHEMBL10614078 | 0.92 | SMN1; SMN2 (0.43) | SMN1; SMN2NPC1LMNANFKB1NFKB2 | |
| SCHEMBL6872017 | 0.89 | ALDH1A1 (0.52) | TSHRSMN1; SMN2NPC1LMNANFKB1 | |
| SCHEMBL6872611 | 0.89 | ALDH1A1 (0.52) | TSHRSMN1; SMN2NPC1LMNANFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-1211552-A | — | — | None | — | — | JP | disclosed |
| US-5324451-A | Excellent response and memory | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1994-06-28 | — | — | US | disclosed |
| EP-0329153-B1 | NOVEL LACTIC ACID DERIVATIVES AND LIQUID CRYSTAL COMPOSITIONS CONTAINING THE SAME | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1992-10-21 | — | — | EP | disclosed |
| JP-H01211552-A | LIQUID CRYSTAL COMPOUND INDUCING EXTREMELY LARGE SPONTANEOUS POLARIZATION | DAINIPPON INK & CHEM INC | 1989-08-24 | — | — | JP | disclosed |