Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | PHGDH | O43175 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.40 |
| ▸ | KIF11 | P52732 | 2/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | ME1 | P48163 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9107918 | 0.85 | P2RX7 (0.54) | KDM4EL3MBTL1P2RX7ALDH1A1 | |
| SCHEMBL9107908 | 0.85 | P2RX7 (0.54) | KDM4EL3MBTL1P2RX7ALDH1A1 | |
| SCHEMBL630463 | 0.84 | P2RX7 (0.51) | MEN1KMT2AP2RX7PHGDH | |
| SCHEMBL289664 | 0.84 | P2RX7 (0.51) | MEN1KMT2AP2RX7PHGDH | |
| SCHEMBL289579 | 0.84 | P2RX7 (0.51) | MEN1KMT2AP2RX7PHGDH | |
| SCHEMBL9107234 | 0.84 | P2RX7 (0.51) | POLBMEN1KMT2AL3MBTL1P2RX7 | |
| SCHEMBL13285257 | 0.84 | P2RX7 (0.42) | KDM4EMEN1KMT2AL3MBTL1P2RX7 | |
| SCHEMBL9107221 | 0.84 | P2RX7 (0.51) | POLBMEN1KMT2AL3MBTL1P2RX7 | |
| SCHEMBL9341749 | 0.83 | KDM4E (0.41) | KDM4EPOLBMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL13284935 | 0.81 | ESR1 (0.46) | KMT2AP2RX7PHGDHESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5362879-A | 4-5-diphenyloxazole derivatives as inhibitors of blood platelet aggregation | BRISTOL-MYERS SQUIBB COMPANY (US) | 1994-11-08 | — | — | US | disclosed |