Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 2/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9343558 | 1.00 | CHRM2 (0.37) | CHRM2CHRM3CHRM4CHRM5CHRM1 | |
| SCHEMBL2449018 | 1.00 | CHRM2 (0.37) | CHRM2CHRM3CHRM4CHRM5CHRM1 | |
| SCHEMBL9740958 | 0.87 | — | — | |
| SCHEMBL7153979 | 0.74 | — | — | |
| SCHEMBL9214995 | 0.72 | — | — | |
| SCHEMBL872855 | 0.71 | — | — | |
| SCHEMBL12657856 | 0.71 | — | — | |
| SCHEMBL232761 | 0.69 | — | — | |
| SCHEMBL8751150 | 0.69 | — | — | |
| SCHEMBL8751032 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0362645-B1 | Use of pteridines in the prevention of the primary and secondary resistance during chemotherapy, and medicaments containing these compounds | THOMAE GMBH DR K (DE) | 1994-06-08 | — | — | EP | disclosed |