Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18241123 | 0.89 | LMNA (0.40) | LMNAGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL27687148 | 0.85 | LMNA (0.35) | LMNAALDH1A1 | |
| SCHEMBL8735194 | 0.84 | GAA (0.31) | GAACA1CA2CA9 | |
| SCHEMBL12232722 | 0.77 | NQO1 (0.36) | CA1CA2CA9SMN1; SMN2 | |
| SCHEMBL27706397 | 0.76 | GRIN2D (0.43) | LMNAGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL28165391 | 0.74 | ERN1 (0.33) | CA1CA2CA9ALDH1A1 | |
| SCHEMBL16291780 | 0.74 | NQO1 (0.38) | SMN1; SMN2 | |
| SCHEMBL18241122 | 0.73 | ERN1 (0.35) | CA1CA2CA9ALDH1A1 | |
| SCHEMBL6568843 | 0.71 | HSD17B10 (0.32) | CA1CA2CA9ALDH1A1 | |
| SCHEMBL10729785 | 0.70 | CA1 (0.37) | CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5348677-A | Electro-optical liquid crystal display element | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1994-09-20 | — | — | US | disclosed |
| US-5196140-A | ELECTRO-OPTICAL LIQUID CRYSTAL DISPLAY ELEMENT | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1993-03-23 | — | — | US | disclosed |
| EP-0313604-B1 | ELECTRO-OPTICAL LIQUID CRYSTAL DISPLAY ELEMENT | MERCK PATENT GmbH (DE) | 1992-03-25 | — | — | EP | disclosed |
| EP-0313604-A1 | ELECTRO-OPTICAL LIQUID CRYSTAL DISPLAY ELEMENT. | MERCK PATENT GMBH (DE) | 1989-05-03 | — | — | EP | disclosed |
| WO-1988008441-A1 | ELECTRO-OPTICAL LIQUID CRYSTAL DISPLAY ELEMENT | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1988-11-03 | — | — | WO | disclosed |