Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | CASP3 | P42574 | 3/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | GLS | O94925 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ELANE | P08246 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14928796 | 0.90 | ALDH1A1 (0.49) | ALDH1A1KMT2ACASP3CA12CA9 | |
| SCHEMBL14393320 | 0.90 | ALDH1A1 (0.49) | ALDH1A1KMT2ACASP3CA12CA9 | |
| SCHEMBL14928649 | 0.90 | ALDH1A1 (0.49) | ALDH1A1KMT2ACASP3CA12CA9 | |
| SCHEMBL7296253 | 0.90 | ALDH1A1 (0.49) | ALDH1A1KMT2ACASP3CA12CA9 | |
| SCHEMBL14928576 | 0.88 | ELANE (0.53) | ALDH1A1KMT2ACASP3CA12CA9 | |
| SCHEMBL14318320 | 0.88 | ALDH1A1 (0.47) | ALDH1A1KMT2ACASP3CA12CA9 | |
| SCHEMBL19938086 | 0.88 | ALDH1A1 (0.47) | ALDH1A1KMT2ACASP3CA12CA9 | |
| SCHEMBL15785094 | 0.88 | ALDH1A1 (0.51) | ALDH1A1KMT2ACA12CA9MAPK1 | |
| SCHEMBL2599263 | 0.88 | ALDH1A1 (0.47) | ALDH1A1KMT2ACASP3CA12CA9 | |
| SCHEMBL10210078 | 0.88 | ELANE (0.53) | ALDH1A1KMT2ACASP3CA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5356932-A | Methods and compositions for controlling intraocular pressure with transition metal complexes | ALCON LABORATORIES, INC. (US) | 1994-10-18 | — | — | US | disclosed |