Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 9/20 | 0.52 |
| ▸ | BACE2 | Q9Y5Z0 | 4/20 | 0.52 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.52 |
| ▸ | TFPI | P10646 | 1/20 | 0.49 |
| ▸ | CASP1 | P29466 | 2/20 | 0.49 |
| ▸ | F2 | P00734 | 2/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | CASP9 | P55211 | 1/20 | 0.49 |
| ▸ | NPY1R | P25929 | 1/20 | 0.49 |
| ▸ | NPY2R | P49146 | 1/20 | 0.49 |
| ▸ | NPY4R | P50391 | 1/20 | 0.49 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.49 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.49 |
| ▸ | CTSD | P07339 | 1/20 | 0.48 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.47 |
| ▸ | GNPAT | O15228 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9341200 | 1.00 | BACE1 (0.52) | BACE1BACE2NAALAD2TFPICASP1 | |
| SCHEMBL24739787 | 0.94 | CASP1 (0.53) | BACE1BACE2CASP1F2CASP3 | |
| SCHEMBL26655866 | 0.94 | CASP1 (0.53) | BACE1BACE2CASP1F2CASP3 | |
| SCHEMBL9341191 | 0.94 | NPY1R (0.51) | BACE1BACE2TFPICASP1NPY1R | |
| SCHEMBL29611494 | 0.93 | BACE1 (0.58) | BACE1BACE2TFPICASP1F2 | |
| SCHEMBL30974007 | 0.91 | ERAP2 (0.52) | BACE1BACE2NAALAD2CASP1F2 | |
| SCHEMBL29611329 | 0.91 | CASP1 (0.55) | BACE1BACE2TFPICASP1F2 | |
| SCHEMBL29611743 | 0.90 | BACE1 (0.51) | BACE1BACE2NAALAD2CASP1F2 | |
| SCHEMBL29719638 | 0.89 | NAALAD2 (0.54) | NAALAD2TFPIF2NPY1RNPY2R | |
| SCHEMBL29612060 | 0.89 | BACE1 (0.59) | BACE1BACE2TFPICASP1F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0307553-B1 | Modified splenopentines, their process of preparation and their use | BERLIN CHEMIE AG (DE) | 1994-06-15 | — | — | EP | claimed |