SCHEMBL9341891

SCHEMBL9341891

CSc1ccc(C(=O)/C=C/c2ccc(O)c(O)c2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.71
MEN1 O00255 2/20 0.71
ALDH1A1 P00352 2/20 0.71
LMNA P02545 2/20 0.71
RAB9A P51151 2/20 0.71
KMT2A Q03164 2/20 0.71
GAA P10253 1/20 0.71
CASP3 P42574 1/20 0.71
SENP8 Q96LD8 1/20 0.71
SENP7 Q9BQF6 1/20 0.71
SENP6 Q9GZR1 1/20 0.71
SNCA P37840 2/20 0.69
TERT O14746 1/20 0.69
CXCL12 P48061 1/20 0.67
NPC1 O15118 1/20 0.65
NFKB1 P19838 1/20 0.65
HTT P42858 1/20 0.65
NFKB2 Q00653 1/20 0.65
RELA Q04206 1/20 0.65
SMN1; SMN2 Q16637 1/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30039604 1.00 MAPT (0.71) MAPTMEN1ALDH1A1LMNARAB9A
SCHEMBL9341898 1.00 MAPT (0.71) MAPTMEN1ALDH1A1LMNARAB9A
SCHEMBL28600841 0.89 MAPT (0.68) MAPTMEN1ALDH1A1LMNARAB9A
SCHEMBL25198279 0.87 MKNK2 (0.68) MAPTMEN1ALDH1A1LMNARAB9A
SCHEMBL30039492 0.87 MAPT (0.66) MAPTMEN1ALDH1A1LMNARAB9A
SCHEMBL30384766 0.87 MAPT (0.66) MAPTMEN1ALDH1A1LMNARAB9A
SCHEMBL25198108 0.87 MAPT (0.66) MAPTMEN1ALDH1A1LMNARAB9A
SCHEMBL25204032 0.87 MAPT (0.66) MAPTMEN1ALDH1A1LMNARAB9A
SCHEMBL30383138 0.87 MKNK2 (0.68) MAPTMEN1ALDH1A1LMNARAB9A
SCHEMBL4461040 0.87 MAPT (0.66) MAPTMEN1ALDH1A1LMNARAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YEWSAVIN INC (US) 2026-01-15 US disclosed
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 US disclosed
EP-4429763-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS Yewsavin, Inc. (US) 2024-09-18 EP disclosed
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-06-22 US disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 WO disclosed
CN-113230240-B 1,3-diphenylprop-2-en-1-one derivative and application thereof 广州医科大学 2022-12-27 CN disclosed
CN-113230240-A 1, 3-diphenylprop-2-en-1-one derivative and application thereof 广州医科大学 2021-08-10 CN disclosed
EP-0328668-B1 NONLINEAR OPTICAL MATERIAL NIPPON OILS & FATS CO LTD (JP) 1994-05-25 EP disclosed
US-5045239-A Chalcone derivative NIPPON OIL AND FATS CO., LTD. (JP) 1991-09-03 US disclosed
EP-0328669-A1 CHALCONE DERIVATIVE COMPOUNDS NIPPON OIL AND FATS COMPANY, LIMITED (JP) 1989-08-23 EP disclosed
EP-0328668-A1 NONLINEAR OPTICAL MATERIAL NIPPON OIL AND FATS COMPANY, LIMITED (JP) 1989-08-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, F2, F13B MAPT 3297/4885MEN1 3367/4885ALDH1A1 3285/4885
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS SERPINC1, SERPINE1, SERPINH1 MAPT 3512/4885MEN1 2457/4885ALDH1A1 3081/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 MAPT 3512/4885MEN1 2457/4885ALDH1A1 3081/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.